CCDC88C

gene product
DAPLE, HkRP2, KIAA1509, SCA40
This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013]
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AntibodyRefsTypeAVIWBELICCIPIHCFC
Invitrogen Antibodies
1 antibody
LifeSpan BioSciences, Inc.
1 antibody
Abnova Corporation
1 antibody
Atlas Antibodies
1 antibody
Novus Biologicals
1 antibody
Bethyl Laboratories
1 antibody
Creative Diagnostics
1 antibody
Sigma-Aldrich
1 antibody
antibodies-online
1 antibody