BS7404

antibody from Bioworld Technology, Inc
Targeting: CCND2
Provider product page for BS7404
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7404 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Cyclin D2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CCND2.
Description
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CCND2 protein structure - BS7404 shown in red.