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- References [193]
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- Product number
- 14642-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14642-1-AP, RRID:AB_2122782
- Product name
- IGF2BP3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IGF2BP3 antibody (Cat. #14642-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RBM15 Enhances 5-Fluorouracil Drug Sensitivity and Suppresses Gastric Cancer Progression by Modulating N6-Methyladenosine Modification of ECT2-Dependent IGF2BP3.
A new mechanism regulating microglial NLRP3 inflammasome: FMR1 mediates NLRP3 mRNA stability.
M6A reader IGF2BP3 stabili1zes SLC7A11 to antagonize ferroptosis and promote gastric tumorigenesis.
LncRNA EGFR-AS1 inhibits ferroptosis to reduce radiosensitivity of cervical cancer through the m6A/IGF2BP3/APAF1 axis.
N(6)-methyladenosine attenuates tumor-associated macrophages M2 polarization via suppressing the translation of Snail.
TOP2A, Stabilized by IGF2BP3 in an m6A-Dependent Manner, Drives Macrophage Recruitment and M2 Polarization in Hepatocellular Carcinoma by YAP1-Mediated CCL2 Activation.
Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes.
IGF2BP3 Promotes Head and Neck Squamous Cell Carcinoma Progression via the M6A-LDHA-Lactate-H4K8la Axis and E2F2 Activation.
VIRMA/IGF2BP3-mediated ANLN upregulation promotes intrahepatic cholangiocarcinoma growth by forming a positive feedback loop with RhoA/YAP1/TEAD1 signaling pathway.
USP5 inhibition stimulates immunogenic ferroptosis that enhances immunotherapy in diffuse large B-cell lymphoma.
METTL3-mediated m(6)A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca(2+) signaling.
IGF2BP3/m6A-mediated intron retention isoform of DUSP6 promotes cisplatin resistance in nasopharyngeal carcinoma by inhibiting pyroptosis.
Development and external validation of a mitophagy-related diagnostic model for biliary atresia based on cellular infiltration patterns.
CircRNA-TMEM71 Inhibits Human Aortic Smooth Muscle Cell Ferroptosis and Prevents Aortic Dissection Formation Through IGF2BP3-Mediated Stability of FSP1.
Identification of IGF2BP3 for the Expression and Prognosis in Gastrointestinal Cancers.
WTAP Maintains Alternative Activation of Macrophages by Promoting IDH1-Mediated α-ketoglutarate Production.
METTL16 Promotes Lipid Metabolic Reprogramming and Colorectal Cancer Progression.
CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway.
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis.
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Core transcriptional regulatory circuit-regulated IGF2BP3 stabilizes E2F2 mRNA via m6A modification in neuroblastoma.
3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay.
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
Interaction between IGF2BP3 and RP11-480I12.5 facilitates proliferation and suppresses apoptosis in non-small cell lung cancer.
ADAP-METTL3 modulates the inflammatory responses of macrophages via m(6)A modification of Spry1.
IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation.
Hsa_circ_0038737 promotes PARPi resistance in castration-resistant prostate cancer via IGF2BP3-mediated DNPH1 mRNA stabilization.
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Hsa_circ_0003611 hinders the transformation of mesenchymal stem cells into osteosarcoma cells through suppressing MYC by IGF2BP3 via m(6)A modification.
Positive feedback loop of IGF2BP3/IL6ST/STAT3 facilitates malignant progression in colorectal cancer.
Hepatitis B Virus Promotes Angiogenesis in Hepatocellular Carcinoma by Increasing m6A Modification of VEGFA mRNA via IGF2BP3.
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
SENP1-mediated deSUMOylation of YBX1 promotes colorectal cancer development through the SENP1-YBX1-AKT signaling axis.
m(6)A/IGF2BP3-driven serine biosynthesis fuels AML stemness and metabolic vulnerability.
Pathological α-synuclein dysregulates epitranscriptomic writer METTL3 to drive neuroinflammation in microglia.
HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity.
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
HaloPROTAC3 treatment activates the unfolded protein response of the endoplasmic reticulum in nonengineered mammalian cell lines.
Triple‑negative breast cancer cell‑derived piR‑31115 promotes the proliferation and migration of endothelial cells via METTL3‑mediated m6A modification of YAP1.
BRD4 regulates m(6)A of ESPL1 mRNA via interaction with ALKBH5 to modulate breast cancer progression.
RETRACTED: Exploring the tumor microenvironment: Chemokine-related genes and immunotherapy/chemotherapy response in clear-cell renal cell carcinoma.
High‑dose sodium propionate contributes to tumor immune escape through the IGF2BP3/PD‑L1 axis in colorectal cancer.
FTO-mediated m(6)A demethylation regulates IGFBP3 expression and AKT activation through IMP3-dependent P-body re-localisation in lung cancer.
IGF2BP2 binding to CPSF6 facilitates m6A-mediated alternative polyadenylation of PUM2 and promotes malignant progression in ovarian cancer.
The promoting effect of the POU3F2/METTL16/PFKM cascade on glycolysis and tumorigenesis of hepatocellular carcinoma.
A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing IGF2BP2-mediated c-MYC translation in TNBC.
The m6A hypermethylation-induced PIR overexpression regulates H3K4me3 and promotes tumorigenesis of uveal melanoma.
ALKBH5-Mediated m(6)A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway.
WTAP/IGF2BP3 Mediated m6A Modification of SOD2 mRNA Aggravates the Tumourigenesis of Colorectal Cancer.
LIN28A-dependent lncRNA NEAT1 aggravates sepsis-induced acute respiratory distress syndrome through destabilizing ACE2 mRNA by RNA methylation.
Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation.
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
METTL3 inhibition promotes radiosensitivity in hepatocellular carcinoma through regulation of SLC7A11 expression.
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis.
METTL14-mediated m6A modification of ZFP14 inhibits clear cell renal cell carcinoma progression via promoting STAT3 ubiquitination.
SREBP1c-Mediated Transcriptional Repression of YME1L1 Contributes to Acute Kidney Injury by Inducing Mitochondrial Dysfunction in Tubular Epithelial Cells.
IGF2BP3-STAT3-METTL3 axis promotes malignant progression in hepatocellular carcinoma (HCC).
The cancer-testis lncRNA LINC01940 promotes gastric cancer malignant progression and chemoresistance by enhancing ribosome biogenesis via TAF15-mediated NOL11 SUMOylation.
IGF2BP3 binds to FBXO32 to activate the cyclic guanosine monophosphate-protein kinase G pathway, promoting gastric cancer progression.
Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8-AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma.
GPCPD1 is regulated by METTL3/IGF2BP3 dependent m(6)A modification to affect pig muscle fiber type conversion.
Polystyrene microspheres could inhibit the ferroptosis of prostate cancer cells via USP39/IGF2BP3/MAPK4 axis.
IGF2BPs-regulated TIN2 confers the malignant biological behaviors of gastric cancer cells.
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Synonymous mutations promote tumorigenesis by disrupting m(6)A-dependent mRNA metabolism.
IGF2BP3 recruits NUDT21 to regulate SPTBN1 alternative polyadenylation and drive ovarian cancer progression.
The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer.
IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming.
The FTO Mediated N6-Methyladenosine Modification of DDIT4 Regulation with Tumorigenesis and Metastasis in Prostate Cancer.
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
m(6)A modification enhances the stability of CDC25A promotes tumorigenicity of esophagogastric junction adenocarcinoma via cell cycle.
IGF2BP3 regulates the expression of RRM2 and promotes the progression of rheumatoid arthritis via RRM2/Akt/MMP-9 pathway.
Comprehensive analysis of IGF2BP3 with expression features, prognosis, immune modulation and stemness in hepatocellular carcinoma and pan-cancer.
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Knockdown of IGF2BP3 Down-Regulates PDCD4 Levels to Attenuate Hypoxic-Ischemic Brain Damage.
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia.
IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism.
m6A modification of VEGFA mRNA by RBM15/YTHDF2/IGF2BP3 contributes to angiogenesis of hepatocellular carcinoma.
IGF2BP3/NCBP1 complex inhibits renal tubular senescence through regulation of CDK6 mRNA stability.
Licochalcone A decreases cancer cell proliferation and enhances ferroptosis in acute myeloid leukemia through suppressing the IGF2BP3/MDM2 cascade.
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Comprehensive proteogenomic characterization of rare kidney tumors.
Protein expression patterns and metal metabolites in a protogynous hermaphrodite fish, the ricefield eel (Monopterus albus).
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice.
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
N6-methyladenosine-modified CircPSMA7 enhances bladder cancer malignancy through the miR-128-3p/MAPK1 axis.
Polypyrimidine tract-binding protein 3/insulin-like growth factor 2 mRNA-binding proteins 3/high-mobility group A1 axis promotes renal cancer growth and metastasis.
Insights into the role of the N6-methyladenosine reader IGF2BP3 in the progression of oral squamous cell carcinoma and its connection to cell-cycle control.
Inhibition of METTL3 in macrophages provides protection against intestinal inflammation.
m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure.
Liver cancer initiation requires translational activation by an oncofetal regulon involving LIN28 proteins.
Systematic analysis of IGF2BP family members in non-small-cell lung cancer.
WTAP/IGF2BP3-mediated GBE1 expression accelerates the proliferation and enhances stemness in pancreatic cancer cells via upregulating c-Myc.
BIRC5 facilitates cisplatin-chemoresistance in a m(6)A-dependent manner in ovarian cancer.
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre-mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis.
IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD.
HNRNPH1 stabilizes FLOT2 mRNA in a non-canonical m6A-dependent manner to promote malignant progression in nasopharyngeal carcinoma.
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage.
The miR-6240 target gene Igf2bp3 promotes myoblast fusion by enhancing myomaker mRNA stability.
N6-Methyladenosine modification activates the serine synthesis pathway to mediate therapeutic resistance in liver cancer.
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
IGF2BP3 Regulates TMA7-mediated Autophagy and Cisplatin Resistance in Laryngeal Cancer via m6A RNA Methylation.
Long Non-coding RNA Linc01224 Regulates Hypopharyngeal Squamous Cell Carcinoma Growth Through Interactions with miR-485-5p and IGF2BP3.
Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancer.
METTL3 regulates alternative splicing of cell cycle-related genes via crosstalk between mRNA m(6)A modifications and splicing factors.
IGF2BP3-mediated regulation of GLS and GLUD1 gene expression promotes treg-induced immune escape in human cervical cancer.
RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA.
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.
The effect of hormones insulin and glucagon on ubiquitin modifications elucidated by proteomics in liver cells.
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization.
Optimized infrared photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (IR-PAR-CLIP) protocol identifies novel IGF2BP3-interacting RNAs in colon cancer cells.
The IGF2BP3-COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression.
Ascorbic acid protects retinal pigment epithelial cells from high glucose by inhibiting the NF-κB signal pathway through MALAT1/IGF2BP3 axis.
RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation.
Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases.
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Comprehensive transcriptomic profiling and mutational landscape of primary gastric linitis plastica.
Methyltransferase-like 3 promotes cervical cancer metastasis by enhancing cathepsin L mRNA stability in an N6-methyladenosine-dependent manner.
N(6)-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice.
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
CircGNB1 facilitates the malignant phenotype of GSCs by regulating miR-515-5p/miR-582-3p-XPR1 axis.
Fusobacterium nucleatum stimulates cell proliferation and promotes PD-L1 expression via IFIT1-related signal in colorectal cancer.
The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells.
Characterization of circSCL38A1 as a novel oncogene in bladder cancer via targeting ILF3/TGF-β2 signaling axis.
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
circRARS synergises with IGF2BP3 to regulate RNA methylation recognition to promote tumour progression in renal cell carcinoma.
m(6)A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3.
IGF2BP1 facilitates non-small cell lung cancer progression by regulating the KIF2A-mediated Wnt/β-catenin pathway.
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
IGF2BP3/HIF1A/YAP signaling plays a role in driving acute-on-chronic liver failure through activating hepatocyte reprogramming.
A lncRNA from the FTO locus acts as a suppressor of the m(6)A writer complex and p53 tumor suppression signaling.
ZXDC enhances cervical cancer metastasis through IGF2BP3-mediated activation of RhoA/ROCK signaling.
UBE2K regulated by IGF2BP3 promotes cell proliferation and stemness in pancreatic ductal adenocarcinoma.
Comprehensive analyses of molecular features, prognostic values, and regulatory functionalities of m(6)A-modified long non-coding RNAs in lung adenocarcinoma.
Epitranscriptic regulation of HRAS by N(6)-methyladenosine drives tumor progression.
N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma.
Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation.
m6A Regulatory Gene-Mediated Methylation Modification in Glioma Survival Prediction.
Diagnostic gene signatures and aberrant pathway activation based on m6A methylation regulators in rheumatoid arthritis.
A pan-cancer landscape of IGF2BPs and their association with prognosis, stemness and tumor immune microenvironment.
IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N(6)-methyladenosine-dependent binding.
CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.
The "m6A writer" METTL3 and the "m6A reader" IGF2BP2 regulate cutaneous T-cell lymphomas progression via CDKN2A.
m(6)A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer.
Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation.
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
CircRNA AFF4 induced by KDM1A promotes osteogenic differentiation through FNDC5/Irisin pathway.
m6A methylated EphA2 and VEGFA through IGF2BP2/3 regulation promotes vasculogenic mimicry in colorectal cancer via PI3K/AKT and ERK1/2 signaling.
N(6)-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition.
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
IGF2BP3 promotes cell metastasis and is associated with poor patient survival in nasopharyngeal carcinoma.
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability.
The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription.
Methyltransferase-like 14 suppresses growth and metastasis of renal cell carcinoma by decreasing long noncoding RNA NEAT1.
Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification.
Matr3 reshapes m6A modification complex to alleviate macrophage inflammation during atherosclerosis.
METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma.
Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Promotes Cell Proliferation of Malignant Mesothelioma Cells by Downregulating p27(Kip1).
Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression.
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
linc01305 promotes metastasis and proliferation of esophageal squamous cell carcinoma through interacting with IGF2BP2 and IGF2BP3 to stabilize HTR3A mRNA.
EGR2-mediated regulation of m(6)A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization.
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development.
LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription.
Clinicopathologic Characteristics of Thyroid Nodules Positive for the THADA-IGF2BP3 Fusion on Preoperative Molecular Analysis.
Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma.
Stabilization of oncogenic transcripts by the IGF2BP3/ELAVL1 complex promotes tumorigenicity in colorectal cancer.
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation.
EIF4G1 and RAN as Possible Drivers for Malignant Pleural Mesothelioma.
N(6)-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance.
Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells.
FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression.
RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts.
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase.
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target.
C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis.
Role of IGF2BP3 in trophoblast cell invasion and migration.
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models.
Characterization and analysis of the composition and dynamics of the mammalian riboproteome.
The distribution of IGF2 and IMP3 in osteosarcoma and its relationship with angiogenesis.
Zhu X, Chen H, Xu K, Liu Y, Li H, Sang Y, Zhao Y, Liu X, Wang X, Cui X, Cai B, Shang L, Jing C, Chong W, Li L
Research (Washington, D.C.) 2026;9:1108
Research (Washington, D.C.) 2026;9:1108
A new mechanism regulating microglial NLRP3 inflammasome: FMR1 mediates NLRP3 mRNA stability.
Deng Q, Bai Q, Yang Y, Tang W, Liu F, Zhang S, Wang H, Xing Z, Zhang C, Yang Y, Fu Q, Fan H
PloS one 2026;21(2):e0341867
PloS one 2026;21(2):e0341867
M6A reader IGF2BP3 stabili1zes SLC7A11 to antagonize ferroptosis and promote gastric tumorigenesis.
Yang Y, Ye H, Qin S, Lin M, Liu Y, Li X
Cellular signalling 2026 Mar;139:112295
Cellular signalling 2026 Mar;139:112295
LncRNA EGFR-AS1 inhibits ferroptosis to reduce radiosensitivity of cervical cancer through the m6A/IGF2BP3/APAF1 axis.
Chen X, Li J, Sun Y, Ye Z, Long M, Bu J, Fan Z, Jiang Z
BMC cancer 2026 Mar 5;26(1)
BMC cancer 2026 Mar 5;26(1)
N(6)-methyladenosine attenuates tumor-associated macrophages M2 polarization via suppressing the translation of Snail.
Tian Y, Peng J, Zhou J, Yang W, Peng Y, Li J, Rui Y, Zhang H, Xie G, Wang H, Wang J, Li J, Huang Z, Ma X, Wang H, He J
Science China. Life sciences 2026 Jan;69(1):119-135
Science China. Life sciences 2026 Jan;69(1):119-135
TOP2A, Stabilized by IGF2BP3 in an m6A-Dependent Manner, Drives Macrophage Recruitment and M2 Polarization in Hepatocellular Carcinoma by YAP1-Mediated CCL2 Activation.
Li L, Du C, Sun N, Xiao X, Li K, Wu H, Gong J
Molecular carcinogenesis 2026 Jan;65(1):123-137
Molecular carcinogenesis 2026 Jan;65(1):123-137
Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes.
Chen X, Sun Z, Chen J, Zhang J, Liu Z, Yan Z, Li Q, Chen Z
International journal of molecular medicine 2026 Jan;57(1)
International journal of molecular medicine 2026 Jan;57(1)
IGF2BP3 Promotes Head and Neck Squamous Cell Carcinoma Progression via the M6A-LDHA-Lactate-H4K8la Axis and E2F2 Activation.
Wu F, Zeng Y, Hu Y, Xie Z, Shen R, Zhou J, Zhou P, Tong S, Liu Y
Technology in cancer research & treatment 2026 Jan-Dec;25:15330338261447338
Technology in cancer research & treatment 2026 Jan-Dec;25:15330338261447338
VIRMA/IGF2BP3-mediated ANLN upregulation promotes intrahepatic cholangiocarcinoma growth by forming a positive feedback loop with RhoA/YAP1/TEAD1 signaling pathway.
Zhang J, Huang N, Gao LR, Guo A, Deng H, Wang L, Liu M
Cell death & disease 2026 Jan 9;17(1):20
Cell death & disease 2026 Jan 9;17(1):20
USP5 inhibition stimulates immunogenic ferroptosis that enhances immunotherapy in diffuse large B-cell lymphoma.
Wu J, Liu C, Chen Q, Deng Y, Wang J, Gao Y, Wei B
Cell communication and signaling : CCS 2026 Jan 5;24(1):93
Cell communication and signaling : CCS 2026 Jan 5;24(1):93
METTL3-mediated m(6)A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca(2+) signaling.
Chen C, Xiong K, Liang F, Zhong Y, Qin X, Huang N, Fang Y, Zhu B, Cheng J, Wei Q, Zheng L, Zhao J
Molecular cancer 2026 Jan 19;25(1)
Molecular cancer 2026 Jan 19;25(1)
IGF2BP3/m6A-mediated intron retention isoform of DUSP6 promotes cisplatin resistance in nasopharyngeal carcinoma by inhibiting pyroptosis.
Li X, Sun X, Gu Q, Long Z, Liu J
BMC cancer 2026 Jan 12;26(1):214
BMC cancer 2026 Jan 12;26(1):214
Development and external validation of a mitophagy-related diagnostic model for biliary atresia based on cellular infiltration patterns.
Sun D, Zhang J, Zhao Y, Li S, Zhang Y, Liao J, Wang D, Hua K, Gu Y, Du J, Zhang S, Huang J
Translational pediatrics 2026 Feb 28;15(2):27
Translational pediatrics 2026 Feb 28;15(2):27
CircRNA-TMEM71 Inhibits Human Aortic Smooth Muscle Cell Ferroptosis and Prevents Aortic Dissection Formation Through IGF2BP3-Mediated Stability of FSP1.
Zhu L, He C, Shi H, Shao G, Sun L
Journal of the American Heart Association 2026 Feb 17;15(4):e043108
Journal of the American Heart Association 2026 Feb 17;15(4):e043108
Identification of IGF2BP3 for the Expression and Prognosis in Gastrointestinal Cancers.
Han F, He C, Qian C, Wang Y, Zhou M, Yang R, Zhang Z
International journal of medical sciences 2025;22(13):3191-3201
International journal of medical sciences 2025;22(13):3191-3201
WTAP Maintains Alternative Activation of Macrophages by Promoting IDH1-Mediated α-ketoglutarate Production.
Xu Q, Zhang J, Zou Y, Chen L, Sun F, Luo X, Wang T, Li Y, Zhang S, Xiong F, Yu Q, Yang P, Gong Q, Liu SW, Wang CY
International journal of biological sciences 2025;21(12):5428-5443
International journal of biological sciences 2025;21(12):5428-5443
METTL16 Promotes Lipid Metabolic Reprogramming and Colorectal Cancer Progression.
Li J, Luo Q, Lu M, Lu C, Xu C, Ding J, Zhan T, Zhu J, Qian M, Lin S, Chang L, Li J, Wang K
International journal of biological sciences 2025;21(11):4782-4797
International journal of biological sciences 2025;21(11):4782-4797
CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway.
Jiang S, Ou L, Wang Y, Su K, Chen Z, He L, Xu X, Cheng B, Xia J, Fan Z
International journal of nanomedicine 2025;20:1597-1613
International journal of nanomedicine 2025;20:1597-1613
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis.
Xu L, Zhang Y, Xing L, Zhou Y, Chang N, Xi H, Xu X, Zhang J
Frontiers in pharmacology 2025;16:1592846
Frontiers in pharmacology 2025;16:1592846
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Shen Y, Wang L, Guo Z, Wang J, Zhang R, Tang C, Wu J
Cellular signalling 2025 Sep;133:111873
Cellular signalling 2025 Sep;133:111873
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Wang T, Han L, Huo Y, Zhang L, Huang Y, Zhang N, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Core transcriptional regulatory circuit-regulated IGF2BP3 stabilizes E2F2 mRNA via m6A modification in neuroblastoma.
Yang P, Wang J, Wu Z, Zhuo R, Chen Y, Li G, Tao Y, Li X, Fang F, Wu D, Yang Y, Yin H, Qian G, Wang H, Li X, Yu J, Yang R, Xu Y, Li Z, Shi L, Zhang Z, Pan J, Wang J
Carcinogenesis 2025 Sep 4;46(3)
Carcinogenesis 2025 Sep 4;46(3)
3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay.
Wu D, Guan X, Yang T, Yan J, Zhu B, Zhou J, Guo Y, Lu Y
Materials today. Bio 2025 Oct;34:102176
Materials today. Bio 2025 Oct;34:102176
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
Yin L, Zhang Y, Zhang B, Zhang J, Xiong M, Jiang N, Xiao J, Gao H, Xiong W, Wang X, Wang F, Yuan S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
Interaction between IGF2BP3 and RP11-480I12.5 facilitates proliferation and suppresses apoptosis in non-small cell lung cancer.
Li R, Gao J, Chen H, Yi J, Yao Y, Liew FF, Li Y
European journal of medical research 2025 Oct 8;30(1):938
European journal of medical research 2025 Oct 8;30(1):938
ADAP-METTL3 modulates the inflammatory responses of macrophages via m(6)A modification of Spry1.
Dong A, Zhang P, Yang F, Wang Y, Liu H
Cell death & disease 2025 Oct 7;16(1):708
Cell death & disease 2025 Oct 7;16(1):708
IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation.
Sharma G, Gutierrez M, Jones AE, Kapoor S, Jaiswal AK, Neeb ZT, Rios A, Dorairaj P, Thaxton ML, Lin TL, Tran TM, Kabbani LES, Ritter AJ, Scherer GM, Sorrentino JP, Stiles L, Hoeve JT, Damoiseaux RD, Garg NK, Divakaruni AS, Sanford JR, Rao DS
Cell reports 2025 Oct 28;44(10):116330
Cell reports 2025 Oct 28;44(10):116330
Hsa_circ_0038737 promotes PARPi resistance in castration-resistant prostate cancer via IGF2BP3-mediated DNPH1 mRNA stabilization.
Wang Z, Ge Q, Anwaier A, Liu S, Tian X, Zhang Z, Feng T, Hong Z, Ye D, Xu W, Qin X
Molecular cancer 2025 Oct 2;24(1):238
Molecular cancer 2025 Oct 2;24(1):238
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Wang J, Deng J, Sun B, Qiao G, Yang J, Gao Z, Zhang Q, Dong M, Qu P, Wang Z
Cellular signalling 2025 Nov;135:112024
Cellular signalling 2025 Nov;135:112024
Hsa_circ_0003611 hinders the transformation of mesenchymal stem cells into osteosarcoma cells through suppressing MYC by IGF2BP3 via m(6)A modification.
Zhang F, Cheng F, He Z, Zhao C
Biological research 2025 Nov 29;59(1):2
Biological research 2025 Nov 29;59(1):2
Positive feedback loop of IGF2BP3/IL6ST/STAT3 facilitates malignant progression in colorectal cancer.
Liu P, Zhou X
Journal of translational medicine 2025 Nov 25;24(1)
Journal of translational medicine 2025 Nov 25;24(1)
Hepatitis B Virus Promotes Angiogenesis in Hepatocellular Carcinoma by Increasing m6A Modification of VEGFA mRNA via IGF2BP3.
Xu X, Zhang Y, Wu S, Wu Y, Lin X, Chen K, Lin X
Journal of medical virology 2025 May;97(5):e70356
Journal of medical virology 2025 May;97(5):e70356
FOXM1-activated IGF2BP3 promotes cell malignant phenotypes and M2 macrophage polarization in hepatocellular carcinoma by inhibiting ferroptosis via stabilizing RRM2 mRNA in an m6A-dependent manner.
Gao H, Shi L, Liu J, Zhao Y, Du F, He Y, Yang X, Song N, Wen J, Zheng G
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
Molecular and cellular biochemistry 2025 May;480(5):3051-3066
SENP1-mediated deSUMOylation of YBX1 promotes colorectal cancer development through the SENP1-YBX1-AKT signaling axis.
Sheng Z, Luo S, Huang L, Deng YN, Zhang N, Luo Y, Zhao X, Chen Y, Li Q, Dai R, Liang S
Oncogene 2025 May;44(19):1361-1374
Oncogene 2025 May;44(19):1361-1374
m(6)A/IGF2BP3-driven serine biosynthesis fuels AML stemness and metabolic vulnerability.
Huang F, Wang Y, Zhang X, Gao W, Li J, Yang Y, Mo H, Prince E, Long Y, Hu J, Jiang C, Kang Y, Chen Z, Hu YC, Zeng C, Yang L, Chen CW, Chen J, Huang H, Weng H
Nature communications 2025 May 6;16(1):4214
Nature communications 2025 May 6;16(1):4214
Pathological α-synuclein dysregulates epitranscriptomic writer METTL3 to drive neuroinflammation in microglia.
Miller C, Ealy A, Gregory A, Janarthanam C, Albers W, Richardson G, Jin H, Zenitsky G, Anantharam V, Kanthasamy A, Kanthasamy AG
Cell reports 2025 May 27;44(5):115618
Cell reports 2025 May 27;44(5):115618
HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity.
Dobersch S, Yamamoto N, Schutter A, Cavender SM, Robertson TM, Kartha N, Samraj AN, Doron B, Poole LA, Wladyka CL, Zhang A, Jang GH, Mahalingam AH, Barreto G, Raghavan S, Narla G, Notta F, Eisenman RN, Hsieh AC, Kugel S
Nature communications 2025 May 26;16(1):4866
Nature communications 2025 May 26;16(1):4866
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
Geng Q, Jiao Y, Diao W, Xu J, Wang Z, Wang X, Wang Z, Zhao L, Yang L, Wang Y, Deng T, Wang B, Xiao C
Bone research 2025 May 12;13(1):51
Bone research 2025 May 12;13(1):51
HaloPROTAC3 treatment activates the unfolded protein response of the endoplasmic reticulum in nonengineered mammalian cell lines.
Anisimova AS, Karagöz GE
Molecular biology of the cell 2025 May 1;36(5):mr3
Molecular biology of the cell 2025 May 1;36(5):mr3
Triple‑negative breast cancer cell‑derived piR‑31115 promotes the proliferation and migration of endothelial cells via METTL3‑mediated m6A modification of YAP1.
Du SM, Li N, Xu WJ, Liu K
Oncology reports 2025 Mar;53(3)
Oncology reports 2025 Mar;53(3)
BRD4 regulates m(6)A of ESPL1 mRNA via interaction with ALKBH5 to modulate breast cancer progression.
Zhang H, Lu L, Yi C, Jiang T, Lu Y, Yang X, Zhong K, Zhou J, Li J, Xie G, Chen Z, Jiang Z, Asadikaram G, Peng Y, Zhou D, Wang H
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1552-1570
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1552-1570
RETRACTED: Exploring the tumor microenvironment: Chemokine-related genes and immunotherapy/chemotherapy response in clear-cell renal cell carcinoma.
Meng Y, Zhang C, Fu T, He J, Wu J, Zhan Y
Environmental toxicology 2025 Jun;40(6):E74-E91
Environmental toxicology 2025 Jun;40(6):E74-E91
High‑dose sodium propionate contributes to tumor immune escape through the IGF2BP3/PD‑L1 axis in colorectal cancer.
Wang X, Hu Y
Oncology letters 2025 Jun;29(6):303
Oncology letters 2025 Jun;29(6):303
FTO-mediated m(6)A demethylation regulates IGFBP3 expression and AKT activation through IMP3-dependent P-body re-localisation in lung cancer.
Wang H, Peng H, Zhang Z, Abulimiti Y, Hu J, Zhou Y, Ji P, Li D
Clinical and translational medicine 2025 Jul;15(7):e70392
Clinical and translational medicine 2025 Jul;15(7):e70392
IGF2BP2 binding to CPSF6 facilitates m6A-mediated alternative polyadenylation of PUM2 and promotes malignant progression in ovarian cancer.
Luo X, Wei Q, Xie L, Chen N, Gu B, Xu J, Jiang X, Zuo X, Zhao H, Liu X, Yang Y, Liu T, Zhu Y, Yi P, Xu J
Clinical and translational medicine 2025 Jul;15(7):e70388
Clinical and translational medicine 2025 Jul;15(7):e70388
The promoting effect of the POU3F2/METTL16/PFKM cascade on glycolysis and tumorigenesis of hepatocellular carcinoma.
Chen M, Yang Y, Hu G, Peng Z, Wen W
Annals of hepatology 2025 Jul-Dec;30(2):101776
Annals of hepatology 2025 Jul-Dec;30(2):101776
A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing IGF2BP2-mediated c-MYC translation in TNBC.
Guo J, Li K, Ming Y, Pan Y, Tan S, Ma H, Chen S, Duan Y, Peng Y
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 8;122(27):e2504320122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 8;122(27):e2504320122
The m6A hypermethylation-induced PIR overexpression regulates H3K4me3 and promotes tumorigenesis of uveal melanoma.
Tian H, Chen Y, Dong X, Fan X, Jia R
Cancer letters 2025 Jul 28;623:217729
Cancer letters 2025 Jul 28;623:217729
ALKBH5-Mediated m(6)A Modification of XBP1 Facilitates NSCLC Progression Through the IL-6-JAK-STAT3 Pathway.
Liang H, Zhang C, Hu M, Hu F, Wang S, Wei W, Hu W
Molecular carcinogenesis 2025 Jan;64(1):57-71
Molecular carcinogenesis 2025 Jan;64(1):57-71
WTAP/IGF2BP3 Mediated m6A Modification of SOD2 mRNA Aggravates the Tumourigenesis of Colorectal Cancer.
Zhou C, Wang M, Du X, Xue L, Zhu X, Li X, Zhao Q
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70117
Journal of biochemical and molecular toxicology 2025 Jan;39(1):e70117
LIN28A-dependent lncRNA NEAT1 aggravates sepsis-induced acute respiratory distress syndrome through destabilizing ACE2 mRNA by RNA methylation.
Liu J, Li X, Yang P, He Y, Hong W, Feng Y, Ye Z
Journal of translational medicine 2025 Jan 6;23(1):15
Journal of translational medicine 2025 Jan 6;23(1):15
Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation.
Yi Y, Wang G, Zhang W, Yu S, Fei J, An T, Yi J, Li F, Huang T, Yang J, Niu M, Wang Y, Xu C, Xiao ZJ
Nature communications 2025 Jan 2;16(1):212
Nature communications 2025 Jan 2;16(1):212
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
Yu A, Wang Y, Duan C, Qin J, Liao M, Zhu H, Lei J, Liu J, Yang Z, Yu L, Gui H, Xin J, Tao W, Bao W, Dong Z
Communications biology 2025 Jan 17;8(1):71
Communications biology 2025 Jan 17;8(1):71
METTL3 inhibition promotes radiosensitivity in hepatocellular carcinoma through regulation of SLC7A11 expression.
Zhang C, Yang T, Chen H, Ding X, Chen H, Liang Z, Zhao Y, Ma S, Liu X
Cell death & disease 2025 Jan 11;16(1):9
Cell death & disease 2025 Jan 11;16(1):9
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis.
Xie X, Li H, Luo B, Fan X, Li Y, Zhang Y, Cui X, Yin W, Liu B, Xu H, Cheng H, Li W, Yu H, Wu F
International immunopharmacology 2025 Jan 10;144:113670
International immunopharmacology 2025 Jan 10;144:113670
METTL14-mediated m6A modification of ZFP14 inhibits clear cell renal cell carcinoma progression via promoting STAT3 ubiquitination.
Liu Z, Sun T, Zhang Z, Piao C, Kong C, Zhang X
Clinical and translational medicine 2025 Feb;15(2):e70232
Clinical and translational medicine 2025 Feb;15(2):e70232
SREBP1c-Mediated Transcriptional Repression of YME1L1 Contributes to Acute Kidney Injury by Inducing Mitochondrial Dysfunction in Tubular Epithelial Cells.
Xin W, Zhou J, Peng Y, Gong S, Liao W, Wang Y, Huang X, Mao Y, Yao M, Qin S, Xiong J, Li Y, Lan Q, Huang Y, Zhao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2412233
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2412233
IGF2BP3-STAT3-METTL3 axis promotes malignant progression in hepatocellular carcinoma (HCC).
Xu Y, Cao Y, Yang J, Yu X, Yang L, Xie Y, Zhao J, Zhang Y
Human genomics 2025 Dec 25;20(1):21
Human genomics 2025 Dec 25;20(1):21
The cancer-testis lncRNA LINC01940 promotes gastric cancer malignant progression and chemoresistance by enhancing ribosome biogenesis via TAF15-mediated NOL11 SUMOylation.
Zang W, Fan D, Lu Z, Gao X, Xing D, Zhang G, Liu L, Yi J, Chen J, Hu Y, Xue W
Cellular & molecular biology letters 2025 Dec 16;31(1):14
Cellular & molecular biology letters 2025 Dec 16;31(1):14
IGF2BP3 binds to FBXO32 to activate the cyclic guanosine monophosphate-protein kinase G pathway, promoting gastric cancer progression.
Si Y, Tian B, Zhang R, Xuan MD, Liu KY, Jiao J, Han SS, Li HF, Hu YH, Zhao HY, He WJ, Wang J, Liu T, Yu WF
World journal of gastroenterology 2025 Dec 14;31(46):111631
World journal of gastroenterology 2025 Dec 14;31(46):111631
Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8-AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma.
Chen ZW, Shan JJ, Chen M, Wu Z, Zhao YM, Zhu HX, Jin X, Wang YX, Wu YB, Xiang Z, Ding ZW, Lin ZH, Wang LR, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e01042
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e01042
GPCPD1 is regulated by METTL3/IGF2BP3 dependent m(6)A modification to affect pig muscle fiber type conversion.
Yang Y, Tan B, Xiao L, Huang H, Xu W, Su J, Zhao Y, Hong L, Cai G, Li Z, Dai L, Gu T
Gene 2025 Aug 20;962:149578
Gene 2025 Aug 20;962:149578
Polystyrene microspheres could inhibit the ferroptosis of prostate cancer cells via USP39/IGF2BP3/MAPK4 axis.
Lu S, Wu R, Li W, Fu Z, Ding X, Luan Y, Tianbao H, Huang Y
Journal of translational medicine 2025 Aug 11;23(1):891
Journal of translational medicine 2025 Aug 11;23(1):891
IGF2BPs-regulated TIN2 confers the malignant biological behaviors of gastric cancer cells.
Li F, Zhou Y, Liao Z, Huang D, Zhang Z, Chen G
Tissue & cell 2025 Apr;93:102716
Tissue & cell 2025 Apr;93:102716
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Min L, Huo F, Zhu Z, Din L, Zhang L, Xu Y, Xing X, Zhang P, Wang Q
Cellular signalling 2025 Apr;128:111649
Cellular signalling 2025 Apr;128:111649
Synonymous mutations promote tumorigenesis by disrupting m(6)A-dependent mRNA metabolism.
Lan Y, Xia Z, Shao Q, Lin P, Lu J, Xiao X, Zheng M, Chen D, Dou Y, Xie Q
Cell 2025 Apr 3;188(7):1828-1841.e15
Cell 2025 Apr 3;188(7):1828-1841.e15
IGF2BP3 recruits NUDT21 to regulate SPTBN1 alternative polyadenylation and drive ovarian cancer progression.
Luo X, Xie L, Ma X, Chen N, Xu J, Jiang X, Liu X, Yang Y, Liu T, Yi P, Xu J
Communications biology 2025 Apr 29;8(1):680
Communications biology 2025 Apr 29;8(1):680
The role of IGF2BP3/SPOP/c-Myc loop in paclitaxel resistance of endometrial cancer.
Ge Y, Kong L, Li Y, Yu Z, Zhai F, Zhan Z, Chen G, Wang S, Wang H, Wang Y, Zhao J, Hu L, Mao J, Wang S, Shi J, Zhao M, Lou P, Ye M, Jin X
Communications biology 2025 Apr 17;8(1):624
Communications biology 2025 Apr 17;8(1):624
IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming.
Gao A, Zou J, Zeng T, Qin M, Tang X, Yi T, Song G, Zhong J, Zeng Y, Zhou W, Gao Q, Zhang Q, Zhang J, Li Y
Cell death & disease 2025 Apr 17;16(1):308
Cell death & disease 2025 Apr 17;16(1):308
The FTO Mediated N6-Methyladenosine Modification of DDIT4 Regulation with Tumorigenesis and Metastasis in Prostate Cancer.
Zhao Y, Hu X, Yu H, Sun H, Zhang L, Shao C
Research (Washington, D.C.) 2024;7:0313
Research (Washington, D.C.) 2024;7:0313
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
Hu Y, Li Y, Xiong H, Zhang Y, Wang F, Zhuo W, Zeng Z, Zhao Y, Wang H, Hu P, Han S, Huang Y, Lv G, Zhao G
International journal of biological sciences 2024;20(11):4341-4363
International journal of biological sciences 2024;20(11):4341-4363
m(6)A modification enhances the stability of CDC25A promotes tumorigenicity of esophagogastric junction adenocarcinoma via cell cycle.
Pan Y, Feng H, Zhou J, Zhang W, Liu Y, Zheng J, Wang J, Gao S, Li Y
International journal of biological sciences 2024;20(11):4209-4221
International journal of biological sciences 2024;20(11):4209-4221
IGF2BP3 regulates the expression of RRM2 and promotes the progression of rheumatoid arthritis via RRM2/Akt/MMP-9 pathway.
Ban Z, Li Z, Xing S, Ye Y
PloS one 2024;19(5):e0303593
PloS one 2024;19(5):e0303593
Comprehensive analysis of IGF2BP3 with expression features, prognosis, immune modulation and stemness in hepatocellular carcinoma and pan-cancer.
Qin S, Jin H, Li Y, Chen X, He J, Xiao J, Qin Y, Liu C, Mao Y, Zhao L
Journal of Cancer 2024;15(9):2845-2865
Journal of Cancer 2024;15(9):2845-2865
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Cai Y, Zhou J, Xu A, Huang J, Zhang H, Xie G, Zhong K, Wu Y, Ye P, Wang H, Niu H
The Journal of biological chemistry 2024 Sep;300(9):107598
The Journal of biological chemistry 2024 Sep;300(9):107598
Knockdown of IGF2BP3 Down-Regulates PDCD4 Levels to Attenuate Hypoxic-Ischemic Brain Damage.
Chen Y, Fang X, Liu H, Fan Q
Frontiers in bioscience (Landmark edition) 2024 Sep 23;29(9):329
Frontiers in bioscience (Landmark edition) 2024 Sep 23;29(9):329
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia.
Yu J, Gao Y, Liu F, Zhang Y, Li J, Ding L, Ren S, Yang J, Jiao J, Feng G, Chen Z, Sun W, Wu J
Journal of nanobiotechnology 2024 Oct 24;22(1):654
Journal of nanobiotechnology 2024 Oct 24;22(1):654
IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism.
Hornegger H, Anisimova AS, Muratovic A, Bourgeois B, Spinetti E, Niedermoser I, Covino R, Madl T, Karagöz GE
Nature communications 2024 Oct 20;15(1):9054
Nature communications 2024 Oct 20;15(1):9054
m6A modification of VEGFA mRNA by RBM15/YTHDF2/IGF2BP3 contributes to angiogenesis of hepatocellular carcinoma.
Xu X, Wu S, Zhang Y, Fan W, Lin X, Chen K, Lin X
Molecular carcinogenesis 2024 Nov;63(11):2174-2189
Molecular carcinogenesis 2024 Nov;63(11):2174-2189
IGF2BP3/NCBP1 complex inhibits renal tubular senescence through regulation of CDK6 mRNA stability.
Li Y, Luo C, Cai Y, Wu Y, Shu T, Wei J, Wang H, Niu H
Translational research : the journal of laboratory and clinical medicine 2024 Nov;273:1-15
Translational research : the journal of laboratory and clinical medicine 2024 Nov;273:1-15
Licochalcone A decreases cancer cell proliferation and enhances ferroptosis in acute myeloid leukemia through suppressing the IGF2BP3/MDM2 cascade.
Han P, Wei S, Wang H, Cai Y
Annals of hematology 2024 Nov;103(11):4511-4524
Annals of hematology 2024 Nov;103(11):4511-4524
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Huang Q, Chu Z, Wang Z, Li Q, Meng S, Lu Y, Ma K, Cui S, Hu W, Zhang W, Wei Q, Qu Y, Li H, Fu X, Zhang C
Nature communications 2024 May 9;15(1):3904
Nature communications 2024 May 9;15(1):3904
Comprehensive proteogenomic characterization of rare kidney tumors.
Li GX, Chen L, Hsiao Y, Mannan R, Zhang Y, Luo J, Petralia F, Cho H, Hosseini N, Leprevost FDV, Calinawan A, Li Y, Anand S, Dagar A, Geffen Y, Kumar-Sinha C, Chugh S, Le A, Ponce S, Guo S, Zhang C, Schnaubelt M, Al Deen NN, Chen F, Caravan W, Houston A, Hopkins A, Newton CJ, Wang X, Polasky DA, Haynes S, Yu F, Jing X, Chen S, Robles AI, Mesri M, Thiagarajan M, An E, Getz GA, Linehan WM, Hostetter G, Jewell SD, Chan DW, Wang P, Omenn GS, Mehra R, Ricketts CJ, Ding L, Chinnaiyan AM, Cieslik MP, Dhanasekaran SM, Zhang H, Nesvizhskii AI, Clinical Proteomic Tumor Analysis Consortium
Cell reports. Medicine 2024 May 21;5(5):101547
Cell reports. Medicine 2024 May 21;5(5):101547
Protein expression patterns and metal metabolites in a protogynous hermaphrodite fish, the ricefield eel (Monopterus albus).
He Z, Xiao F, Yang D, Deng F, Ding W, He Z, Wang S, Chen Q, Wang H, Chen M, Gao K, Xiong J, Tang Z, Zhang M, Yan T
BMC genomics 2024 May 21;25(1):500
BMC genomics 2024 May 21;25(1):500
IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Yuan D, Li H, Dai W, Zhou X, Zhou W, He L
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167022
Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice.
Shen X, Chen M, Zhang J, Lin Y, Gao X, Tu J, Chen K, Zhu A, Xu S
Genes 2024 Mar 9;15(3)
Genes 2024 Mar 9;15(3)
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J
Cell death & disease 2024 Mar 6;15(3):192
Cell death & disease 2024 Mar 6;15(3):192
N6-methyladenosine-modified CircPSMA7 enhances bladder cancer malignancy through the miR-128-3p/MAPK1 axis.
Yi J, Ma X, Ying Y, Liu Z, Tang Y, Shu X, Sun J, Wu Y, Lu D, Wang X, Luo J, Liu B, Zheng X, Lin Y, Li J, Xie L
Cancer letters 2024 Mar 31;585:216613
Cancer letters 2024 Mar 31;585:216613
Polypyrimidine tract-binding protein 3/insulin-like growth factor 2 mRNA-binding proteins 3/high-mobility group A1 axis promotes renal cancer growth and metastasis.
Wang Q, Chen F, He Y, Gao Y, Wang J, Chu S, Xie P, Zhong J, Shan H, Bai J, Hou P
iScience 2024 Mar 15;27(3):109158
iScience 2024 Mar 15;27(3):109158
Insights into the role of the N6-methyladenosine reader IGF2BP3 in the progression of oral squamous cell carcinoma and its connection to cell-cycle control.
Song D, Dai X, Fu M, Sun Y, Wu X, Zhou Q, Bi W, Sun J, Yang F, Yu Y
Translational oncology 2024 Jun;44:101932
Translational oncology 2024 Jun;44:101932
Inhibition of METTL3 in macrophages provides protection against intestinal inflammation.
Yin H, Ju Z, Zhang X, Zuo W, Yang Y, Zheng M, Zhang X, Liu Y, Peng Y, Xing Y, Yang A, Zhang R
Cellular & molecular immunology 2024 Jun;21(6):589-603
Cellular & molecular immunology 2024 Jun;21(6):589-603
m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure.
Ouyang KW, Wang TT, Wang H, Luo YX, Hu YF, Zheng XM, Ling Q, Wang KW, Xiong YW, Zhang J, Chang W, Zhang YF, Yuan Z, Li H, Gao L, Xu DX, Zhu HL, Yang L, Wang H
The Science of the total environment 2024 Jun 25;931:172938
The Science of the total environment 2024 Jun 25;931:172938
Liver cancer initiation requires translational activation by an oncofetal regulon involving LIN28 proteins.
Hsieh MH, Wei Y, Li L, Nguyen LH, Lin YH, Yong JM, Sun X, Wang X, Luo X, Knutson SK, Bracken C, Daley GQ, Powers JT, Zhu H
The Journal of clinical investigation 2024 Jun 13;134(15)
The Journal of clinical investigation 2024 Jun 13;134(15)
Systematic analysis of IGF2BP family members in non-small-cell lung cancer.
Gong L, Liu Q, Jia M, Sun X
Human genomics 2024 Jun 12;18(1):63
Human genomics 2024 Jun 12;18(1):63
WTAP/IGF2BP3-mediated GBE1 expression accelerates the proliferation and enhances stemness in pancreatic cancer cells via upregulating c-Myc.
Jin W, Yao Y, Fu Y, Lei X, Fu W, Lu Q, Tong X, Xu Q, Su W, Hu X
Cellular & molecular biology letters 2024 Jul 3;29(1):97
Cellular & molecular biology letters 2024 Jul 3;29(1):97
BIRC5 facilitates cisplatin-chemoresistance in a m(6)A-dependent manner in ovarian cancer.
Fan Y, Pan Y, Jia L, Gu S, Liu B, Mei Z, Lv C, Huang H, Zhu G, Deng Q
Cancer medicine 2024 Jan;13(1):e6811
Cancer medicine 2024 Jan;13(1):e6811
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
Wang J, Zheng F, Wang D, Yang Q
Cell death & disease 2024 Jan 29;15(1):97
Cell death & disease 2024 Jan 29;15(1):97
Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre-mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis.
Nie D, Tang X, Deng H, Yang X, Tao J, Xu F, Liu Y, Wu K, Wang K, Mei Z, Huang A, Tang N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(5):e2305374
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(5):e2305374
IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD.
Han C, Hu C, Liu T, Sun Y, Hu F, He Y, Zhang J, Chen J, Ding J, Fan J, Zhang X, Wang J, Qiao X, Jiang D, Yang K, Yang S
Cell death & disease 2024 Feb 14;15(2):138
Cell death & disease 2024 Feb 14;15(2):138
HNRNPH1 stabilizes FLOT2 mRNA in a non-canonical m6A-dependent manner to promote malignant progression in nasopharyngeal carcinoma.
Li Q, Liu J, Zeng C, Qin D, Zhang Z, Lv Q, Li J, Huang W
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2279-2295
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2279-2295
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage.
Li F, Wang F, Wang L, Wang J, Wei S, Meng J, Li Y, Feng L, Jiang P
Epigenetics 2024 Dec;19(1):2326868
Epigenetics 2024 Dec;19(1):2326868
The miR-6240 target gene Igf2bp3 promotes myoblast fusion by enhancing myomaker mRNA stability.
Huang Y, Wang W, Fan X, Liu X, Liu W, Wang Z, Li Y, Yang Y, Tang Z
Cellular & molecular biology letters 2024 Dec 5;29(1):152
Cellular & molecular biology letters 2024 Dec 5;29(1):152
N6-Methyladenosine modification activates the serine synthesis pathway to mediate therapeutic resistance in liver cancer.
Chan FF, Kwan KK, Seoung DH, Chin DW, Ng IO, Wong CC, Wong CM
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Dec 4;32(12):4435-4447
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Dec 4;32(12):4435-4447
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Ding P, Wu H, Wu J, Li T, He J, Ju Y, Liu Y, Li F, Deng H, Gu R, Zhang L, Guo H, Tian Y, Yang P, Meng N, Li X, Guo Z, Meng L, Zhao Q
Oncogene 2024 Aug;43(34):2548-2563
Oncogene 2024 Aug;43(34):2548-2563
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
Wu J, Li X, Nie H, Shen Y, Guo Z, Huihan Chu C, Cai K, Tang C
Biochemical pharmacology 2024 Apr;222:116118
Biochemical pharmacology 2024 Apr;222:116118
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
Xiao Y, Liu X, Xie K, Luo J, Zhang Y, Huang X, Luo J, Tan S
Clinical and translational medicine 2024 Apr;14(4):e1653
Clinical and translational medicine 2024 Apr;14(4):e1653
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
Wu S, Dai X, Xia Y, Zhao Q, Zhao H, Shi Z, Yin X, Liu X, Zhang A, Yao Z, Zhang H, Li Q, Thorne RF, Zhang S, Sheng W, Hu W, Gu H
Cell reports 2024 Apr 23;43(4):114111
Cell reports 2024 Apr 23;43(4):114111
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
Zhou Y, Ray PS, Zhu J, Stein F, Rettel M, Sekaran T, Sahadevan S, Perez-Perri JI, Roth EK, Myklebost O, Meza-Zepeda LA, von Deimling A, Fu C, Brosig AN, Boye K, Nathrath M, Blattmann C, Lehner B, Hentze MW, Kulozik AE
Nature communications 2024 Apr 1;15(1):2810
Nature communications 2024 Apr 1;15(1):2810
IGF2BP3 Regulates TMA7-mediated Autophagy and Cisplatin Resistance in Laryngeal Cancer via m6A RNA Methylation.
Yang L, Yan B, Qu L, Ren J, Li Q, Wang J, Kan X, Liu M, Wang Y, Sun Y, Wang C, Wang P
International journal of biological sciences 2023;19(5):1382-1400
International journal of biological sciences 2023;19(5):1382-1400
Long Non-coding RNA Linc01224 Regulates Hypopharyngeal Squamous Cell Carcinoma Growth Through Interactions with miR-485-5p and IGF2BP3.
Wei L, Wu Y, Cai S, Qin Y, Xing S, Wang Z
Journal of Cancer 2023;14(16):3009-3022
Journal of Cancer 2023;14(16):3009-3022
Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancer.
Chen P, Xu J, Cui Z, Wu S, Xie T, Zhang X
Frontiers in immunology 2023;14:1071675
Frontiers in immunology 2023;14:1071675
METTL3 regulates alternative splicing of cell cycle-related genes via crosstalk between mRNA m(6)A modifications and splicing factors.
Kim Y, Shin S, Kwon S, Moon K, Baek SV, Jo A, Kim HS, Hwang GH, Bae S, Kim YH, Cho SY, Oh JM
American journal of cancer research 2023;13(4):1443-1456
American journal of cancer research 2023;13(4):1443-1456
IGF2BP3-mediated regulation of GLS and GLUD1 gene expression promotes treg-induced immune escape in human cervical cancer.
Zhou T, Xiao Z, Lu J, Zhang L, Bo L, Wang J
American journal of cancer research 2023;13(11):5289-5305
American journal of cancer research 2023;13(11):5289-5305
RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA.
Fan J, Zhuang M, Fan W, Hou M
PeerJ 2023;11:e15706
PeerJ 2023;11:e15706
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner.
Zhang X, Shi L, Sun HD, Wang ZW, Xu F, Wei JF, Ding Q
Clinical and translational medicine 2023 Sep;13(9):e1427
Clinical and translational medicine 2023 Sep;13(9):e1427
The effect of hormones insulin and glucagon on ubiquitin modifications elucidated by proteomics in liver cells.
Vemana HP, Dukhande VV
Life sciences 2023 Sep 15;329:121935
Life sciences 2023 Sep 15;329:121935
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Sun X, Ye G, Li J, Shou H, Bai G, Zhang J
Clinical and translational medicine 2023 Oct;13(10):e1457
Clinical and translational medicine 2023 Oct;13(10):e1457
IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization.
Qin J, Cui Z, Zhou J, Zhang B, Lu R, Ding Y, Hu H, Cai J
Translational oncology 2023 Nov;37:101764
Translational oncology 2023 Nov;37:101764
Optimized infrared photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (IR-PAR-CLIP) protocol identifies novel IGF2BP3-interacting RNAs in colon cancer cells.
Anisimova AS, Karagöz GE
RNA (New York, N.Y.) 2023 Nov;29(11):1818-1836
RNA (New York, N.Y.) 2023 Nov;29(11):1818-1836
The IGF2BP3-COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression.
Tang J, Wang S, Weng M, Guo Q, Ren L, He Y, Cui Z, Cong M, Qin M, Yu J, Su R, Li X
Cancer research 2023 Nov 1;83(21):3593-3610
Cancer research 2023 Nov 1;83(21):3593-3610
Ascorbic acid protects retinal pigment epithelial cells from high glucose by inhibiting the NF-κB signal pathway through MALAT1/IGF2BP3 axis.
Tian Y, Cheng W, Wang H, Zeng C, Chen X
Diabetic medicine : a journal of the British Diabetic Association 2023 May;40(5):e15050
Diabetic medicine : a journal of the British Diabetic Association 2023 May;40(5):e15050
RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation.
Zhu K, Gao T, Wang Z, Zhang L, Tan K, Lv Z
Cell death discovery 2023 May 8;9(1):151
Cell death discovery 2023 May 8;9(1):151
Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases.
Kartha N, Gianopulos JE, Schrank Z, Cavender SM, Dobersch S, Kynnap BD, Wallace-Povirk A, Wladyka CL, Santana JF, Kim JC, Yu A, Bridgwater CM, Fuchs K, Dysinger S, Lampano AE, Notta F, Price DH, Hsieh AC, Hingorani SR, Kugel S
Science translational medicine 2023 May 3;15(694):eabn9674
Science translational medicine 2023 May 3;15(694):eabn9674
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Lu Y, Zhang H, Pan H, Zhang Z, Zeng H, Xie H, Yin J, Tang W, Lin R, Zeng C, Cai D
Journal of translational medicine 2023 May 22;21(1):339
Journal of translational medicine 2023 May 22;21(1):339
Comprehensive transcriptomic profiling and mutational landscape of primary gastric linitis plastica.
Liu Z, Hong LL, Zheng JS, Ling ZN, Zhang ZL, Qi YN, Zhang XY, Zhu TY, Wang JL, Han J, Chen XL, Yu QM, Wang S, Li P, Ling ZQ
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2023 Mar;26(2):203-219
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2023 Mar;26(2):203-219
Methyltransferase-like 3 promotes cervical cancer metastasis by enhancing cathepsin L mRNA stability in an N6-methyladenosine-dependent manner.
Liu P, Ju M, Zheng X, Jiang Y, Yu X, Pan B, Luo R, Jia W, Zheng M
Cancer science 2023 Mar;114(3):837-854
Cancer science 2023 Mar;114(3):837-854
N(6)-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice.
Wang X, Ding Y, Li R, Zhang R, Ge X, Gao R, Wang M, Huang Y, Zhang F, Zhao B, Liao W, Du J
Nature communications 2023 Mar 2;14(1):1185
Nature communications 2023 Mar 2;14(1):1185
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Wei W, Zhang ZY, Shi B, Cai Y, Zhang HS, Sun CL, Fei YF, Zhong W, Zhang S, Wang C, He B, Jiang GM, Wang H
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
CircGNB1 facilitates the malignant phenotype of GSCs by regulating miR-515-5p/miR-582-3p-XPR1 axis.
Hu J, Zhang G, Wang Y, Xu K, Chen L, Luo G, Xu J, Li H, Pei D, Zhao X, Guo Z, Li X, Zong S, Jiang Y, Jing Z
Cancer cell international 2023 Jul 5;23(1):132
Cancer cell international 2023 Jul 5;23(1):132
Fusobacterium nucleatum stimulates cell proliferation and promotes PD-L1 expression via IFIT1-related signal in colorectal cancer.
Gao Y, Zou T, Xu P, Wang Y, Jiang Y, Chen YX, Chen H, Hong J, Fang JY
Neoplasia (New York, N.Y.) 2023 Jan;35:100850
Neoplasia (New York, N.Y.) 2023 Jan;35:100850
The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells.
Du P, Meng L, Liao X, Liu Y, Mo X, Gong M, Liao Y
Acta biochimica et biophysica Sinica 2023 Jan 25;55(1):103-116
Acta biochimica et biophysica Sinica 2023 Jan 25;55(1):103-116
Characterization of circSCL38A1 as a novel oncogene in bladder cancer via targeting ILF3/TGF-β2 signaling axis.
Li P, Mi Q, Yan S, Xie Y, Cui Z, Zhang S, Wang Y, Gao H, Wang Y, Li J, Du L, Wang C
Cell death & disease 2023 Jan 25;14(1):59
Cell death & disease 2023 Jan 25;14(1):59
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
Wang Y, Zhang L, Sun XL, Lu YC, Chen S, Pei DS, Zhang LS
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):233-246
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):233-246
circRARS synergises with IGF2BP3 to regulate RNA methylation recognition to promote tumour progression in renal cell carcinoma.
Liu Y, Chen K, Shou Y, Li S, Wang J, Zhang Q, Huang Z, Xu J, Li M, Liu D, Liang H, Yang H, Zhang X
Clinical and translational medicine 2023 Dec;13(12):e1512
Clinical and translational medicine 2023 Dec;13(12):e1512
m(6)A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3.
Shan T, Liu F, Wen M, Chen Z, Li S, Wang Y, Cheng H, Zhou Y
Molecular cell 2023 Dec 21;83(24):4494-4508.e6
Molecular cell 2023 Dec 21;83(24):4494-4508.e6
IGF2BP1 facilitates non-small cell lung cancer progression by regulating the KIF2A-mediated Wnt/β-catenin pathway.
Sun M, Wang L, Ge L, Xu D, Zhang R
Functional & integrative genomics 2023 Dec 15;24(1):4
Functional & integrative genomics 2023 Dec 15;24(1):4
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
Duan Z, Ma L, Jin J, Ma L, Ye L, Wu J, Luo Y
European journal of immunology 2023 Aug;53(8):e2250261
European journal of immunology 2023 Aug;53(8):e2250261
IGF2BP3/HIF1A/YAP signaling plays a role in driving acute-on-chronic liver failure through activating hepatocyte reprogramming.
Cheng K, Liu S, Li C, Zhao Y, Wang Q
Cellular signalling 2023 Aug;108:110727
Cellular signalling 2023 Aug;108:110727
A lncRNA from the FTO locus acts as a suppressor of the m(6)A writer complex and p53 tumor suppression signaling.
Zhang J, Wei J, Sun R, Sheng H, Yin K, Pan Y, Jimenez R, Chen S, Cui XL, Zou Z, Yue Z, Emch MJ, Hawse JR, Wang L, He HH, Xia S, Han B, He C, Huang H
Molecular cell 2023 Aug 3;83(15):2692-2708.e7
Molecular cell 2023 Aug 3;83(15):2692-2708.e7
ZXDC enhances cervical cancer metastasis through IGF2BP3-mediated activation of RhoA/ROCK signaling.
Mao Y, Jiang X, Guo P, Ouyang Y, Chen X, Xia M, Wu L, Tang Z, Liang T, Li Y, He M
iScience 2023 Aug 18;26(8):107447
iScience 2023 Aug 18;26(8):107447
UBE2K regulated by IGF2BP3 promotes cell proliferation and stemness in pancreatic ductal adenocarcinoma.
Fu W, Lei X, Lu Q, Zhang J, Guo J, Zhao J, Tong X, Hu X
International journal of oncology 2023 Apr;62(4)
International journal of oncology 2023 Apr;62(4)
Comprehensive analyses of molecular features, prognostic values, and regulatory functionalities of m(6)A-modified long non-coding RNAs in lung adenocarcinoma.
Ping Y, Huang J, Zhu J, Sun Z, Shang A, Chen C, Liu W, Li D
Clinical epigenetics 2023 Apr 7;15(1):60
Clinical epigenetics 2023 Apr 7;15(1):60
Epitranscriptic regulation of HRAS by N(6)-methyladenosine drives tumor progression.
Pan Y, Gu Y, Liu T, Zhang Q, Yang F, Duan L, Cheng S, Zhu X, Xi Y, Chang X, Ye Q, Gao S
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 4;120(14):e2302291120
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 4;120(14):e2302291120
N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma.
Zheng X, Li S, Yu J, Dai C, Yan S, Chen G, Sun C
Translational cancer research 2023 Apr 28;12(4):992-1005
Translational cancer research 2023 Apr 28;12(4):992-1005
Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation.
Liu Y, Wang X, Zeng X, Wu Y, Liu X, Tan J, Li X
Open medicine (Warsaw, Poland) 2022;17(1):1183-1202
Open medicine (Warsaw, Poland) 2022;17(1):1183-1202
m6A Regulatory Gene-Mediated Methylation Modification in Glioma Survival Prediction.
Zhang G, Zheng P, Lv Y, Shi Z, Shi F
Frontiers in genetics 2022;13:873764
Frontiers in genetics 2022;13:873764
Diagnostic gene signatures and aberrant pathway activation based on m6A methylation regulators in rheumatoid arthritis.
Geng Q, Cao X, Fan D, Gu X, Zhang Q, Zhang M, Wang Z, Deng T, Xiao C
Frontiers in immunology 2022;13:1041284
Frontiers in immunology 2022;13:1041284
A pan-cancer landscape of IGF2BPs and their association with prognosis, stemness and tumor immune microenvironment.
Shao W, Zhao H, Zhang S, Ding Q, Guo Y, Hou K, Kan Y, Deng F, Xu Q
Frontiers in oncology 2022;12:1049183
Frontiers in oncology 2022;12:1049183
IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N(6)-methyladenosine-dependent binding.
Zhang J, Yang K, Bu J, Yan J, Hu X, Liu K, Gao S, Tang S, Gao L, Chen W
Frontiers in oncology 2022;12:1035871
Frontiers in oncology 2022;12:1035871
CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.
Zhang M, Yang C, Ruan X, Liu X, Wang D, Liu L, Shao L, Wang P, Dong W, Xue Y
Communications biology 2022 Sep 5;5(1):908
Communications biology 2022 Sep 5;5(1):908
The "m6A writer" METTL3 and the "m6A reader" IGF2BP2 regulate cutaneous T-cell lymphomas progression via CDKN2A.
Wang X, Hu M, Yu L, Wang X, Jiang X, Zhang G, Ding K
Hematological oncology 2022 Oct;40(4):567-576
Hematological oncology 2022 Oct;40(4):567-576
m(6)A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer.
Tsuchiya K, Yoshimura K, Iwashita Y, Inoue Y, Ohta T, Watanabe H, Yamada H, Kawase A, Tanahashi M, Ogawa H, Funai K, Shinmura K, Suda T, Sugimura H
Cancer gene therapy 2022 Oct;29(10):1355-1372
Cancer gene therapy 2022 Oct;29(10):1355-1372
Senescent neutrophils-derived exosomal piRNA-17560 promotes chemoresistance and EMT of breast cancer via FTO-mediated m6A demethylation.
Ou B, Liu Y, Gao Z, Xu J, Yan Y, Li Y, Zhang J
Cell death & disease 2022 Oct 27;13(10):905
Cell death & disease 2022 Oct 27;13(10):905
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
Jiang T, He X, Zhao Z, Zhang X, Wang T, Jia L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22618
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22618
CircRNA AFF4 induced by KDM1A promotes osteogenic differentiation through FNDC5/Irisin pathway.
Liu A, Chen Y, Zhong D, Wang C, Yu M, Liu C, Yang Z, Chen W, Yin K
Molecular medicine (Cambridge, Mass.) 2022 Nov 18;28(1):134
Molecular medicine (Cambridge, Mass.) 2022 Nov 18;28(1):134
m6A methylated EphA2 and VEGFA through IGF2BP2/3 regulation promotes vasculogenic mimicry in colorectal cancer via PI3K/AKT and ERK1/2 signaling.
Liu X, He H, Zhang F, Hu X, Bi F, Li K, Yu H, Zhao Y, Teng X, Li J, Wang L, Zhang Y, Wu Q
Cell death & disease 2022 May 21;13(5):483
Cell death & disease 2022 May 21;13(5):483
N(6)-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition.
Wu Y, Xu X, Qi M, Chen C, Li M, Yan R, Kou X, Zhao Y, Liu W, Li Y, Liu X, Zhang M, Yi C, Liu H, Xiang J, Wang H, Shen B, Gao Y, Gao S
Nature cell biology 2022 Jun;24(6):917-927
Nature cell biology 2022 Jun;24(6):917-927
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Li Z, Xu Q, Huangfu N, Chen X, Zhu J
Journal of clinical laboratory analysis 2022 Jan;36(1):e24019
Journal of clinical laboratory analysis 2022 Jan;36(1):e24019
IGF2BP3 promotes cell metastasis and is associated with poor patient survival in nasopharyngeal carcinoma.
Xu Y, Guo Z, Peng H, Guo L, Wang P
Journal of cellular and molecular medicine 2022 Jan;26(2):410-421
Journal of cellular and molecular medicine 2022 Jan;26(2):410-421
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability.
Zhang N, Shen Y, Li H, Chen Y, Zhang P, Lou S, Deng J
Experimental & molecular medicine 2022 Feb;54(2):194-205
Experimental & molecular medicine 2022 Feb;54(2):194-205
The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription.
Xia A, Yuan W, Wang Q, Xu J, Gu Y, Zhang L, Chen C, Wang Z, Wu D, He Q, Yu W, Wang F, Xue C, Zhang Y, Bao G, Tao X, Liu S, Wang S, Hu Z, Sun B
Nature cancer 2022 Feb;3(2):203-218
Nature cancer 2022 Feb;3(2):203-218
Methyltransferase-like 14 suppresses growth and metastasis of renal cell carcinoma by decreasing long noncoding RNA NEAT1.
Liu T, Wang H, Fu Z, Wang Z, Wang J, Gan X, Wang A, Wang L
Cancer science 2022 Feb;113(2):446-458
Cancer science 2022 Feb;113(2):446-458
Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification.
Hu Y, Gong C, Li Z, Liu J, Chen Y, Huang Y, Luo Q, Wang S, Hou Y, Yang S, Xiao Y
Molecular cancer 2022 Feb 3;21(1):34
Molecular cancer 2022 Feb 3;21(1):34
Matr3 reshapes m6A modification complex to alleviate macrophage inflammation during atherosclerosis.
Sun Z, Chen W, Wang Z, Wang S, Zan J, Zheng L, Zhao W
Clinical immunology (Orlando, Fla.) 2022 Dec;245:109176
Clinical immunology (Orlando, Fla.) 2022 Dec;245:109176
METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma.
Li HB, Huang G, Tu J, Lv DM, Jin QL, Chen JK, Zou YT, Lee DF, Shen JN, Xie XB
EBioMedicine 2022 Aug;82:104142
EBioMedicine 2022 Aug;82:104142
Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Promotes Cell Proliferation of Malignant Mesothelioma Cells by Downregulating p27(Kip1).
Endo I, Amatya VJ, Kushitani K, Kambara T, Nakagiri T, Fujii Y, Takeshima Y
Frontiers in oncology 2021;11:795467
Frontiers in oncology 2021;11:795467
Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression.
He RZ, Jiang J, Hu X, Lei M, Li J, Luo W, Duan L, Hu Z, Mo YY, Luo DX, Peng WX
Cancer cell international 2021 Nov 22;21(1):616
Cancer cell international 2021 Nov 22;21(1):616
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361
Cell research 2021 Mar;31(3):345-361
linc01305 promotes metastasis and proliferation of esophageal squamous cell carcinoma through interacting with IGF2BP2 and IGF2BP3 to stabilize HTR3A mRNA.
Huang GW, Chen QQ, Ma CC, Xie LH, Gu J
The international journal of biochemistry & cell biology 2021 Jul;136:106015
The international journal of biochemistry & cell biology 2021 Jul;136:106015
EGR2-mediated regulation of m(6)A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization.
Ying Y, Ma X, Fang J, Chen S, Wang W, Li J, Xie H, Wu J, Xie B, Liu B, Wang X, Zheng X, Xie L
Cell death & disease 2021 Jul 29;12(8):750
Cell death & disease 2021 Jul 29;12(8):750
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development.
Yang Y, Fan X, Yan J, Chen M, Zhu M, Tang Y, Liu S, Tang Z
Nucleic acids research 2021 Feb 22;49(3):1313-1329
Nucleic acids research 2021 Feb 22;49(3):1313-1329
LncRNA CDKN2B-AS1 stabilized by IGF2BP3 drives the malignancy of renal clear cell carcinoma through epigenetically activating NUF2 transcription.
Xie X, Lin J, Fan X, Zhong Y, Chen Y, Liu K, Ren Y, Chen X, Lai D, Li X, Li Z, Tang A
Cell death & disease 2021 Feb 19;12(2):201
Cell death & disease 2021 Feb 19;12(2):201
Clinicopathologic Characteristics of Thyroid Nodules Positive for the THADA-IGF2BP3 Fusion on Preoperative Molecular Analysis.
Morariu EM, McCoy KL, Chiosea SI, Nikitski AV, Manroa P, Nikiforova MN, Nikiforov YE
Thyroid : official journal of the American Thyroid Association 2021 Aug;31(8):1212-1218
Thyroid : official journal of the American Thyroid Association 2021 Aug;31(8):1212-1218
Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma.
Liu J, Zhou Z, Ma L, Li C, Lin Y, Yu T, Wei JF, Zhu L, Yao G
Cancer cell international 2021 Aug 26;21(1):453
Cancer cell international 2021 Aug 26;21(1):453
Stabilization of oncogenic transcripts by the IGF2BP3/ELAVL1 complex promotes tumorigenicity in colorectal cancer.
Li K, Huang F, Li Y, Li D, Lin H, Ni R, Zhang Q, Zhao M, Huang S, Zou L, Huang C
American journal of cancer research 2020;10(8):2480-2494
American journal of cancer research 2020;10(8):2480-2494
RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.
Yang Z, Wang T, Wu D, Min Z, Tan J, Yu B
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Journal of experimental & clinical cancer research : CR 2020 Sep 29;39(1):203
Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
Zhang Y, Liu X, Yu M, Xu M, Xiao Y, Ma W, Huang L, Li X, Ye X
Life sciences 2020 Nov 1;260:118413
Life sciences 2020 Nov 1;260:118413
Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation.
Wang LJ, Xue Y, Li H, Huo R, Yan Z, Wang J, Xu H, Wang J, Cao Y, Zhao JZ
Journal of cellular and molecular medicine 2020 May;24(9):4981-4991
Journal of cellular and molecular medicine 2020 May;24(9):4981-4991
EIF4G1 and RAN as Possible Drivers for Malignant Pleural Mesothelioma.
Dell'Anno I, Barbarino M, Barone E, Giordano A, Luzzi L, Bottaro M, Migliore L, Agostini S, Melani A, Melaiu O, Catalano C, Cipollini M, Silvestri R, Corrado A, Gemignani F, Landi S
International journal of molecular sciences 2020 Jul 9;21(14)
International journal of molecular sciences 2020 Jul 9;21(14)
N(6)-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
Du J, Liao W, Liu W, Deb DK, He L, Hsu PJ, Nguyen T, Zhang L, Bissonnette M, He C, Li YC
Developmental cell 2020 Dec 21;55(6):737-753.e7
Developmental cell 2020 Dec 21;55(6):737-753.e7
Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance.
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Jia C, Tang H, Yang Y, Yuan S, Han T, Fang M, Huang S, Hu R, Li C, Geng W
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FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression.
Hong Y, Qin H, Li Y, Zhang Y, Zhuang X, Liu L, Lu K, Li L, Deng X, Liu F, Shi S, Liu G
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RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts.
Wang S, Jung Y, Hyun J, Friedersdorf M, Oh SH, Kim J, Premont RT, Keene JD, Diehl AM
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The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Li Z, Zhang J, Liu X, Li S, Wang Q, Di Chen, Hu Z, Yu T, Ding J, Li J, Yao M, Fan J, Huang S, Gao Q, Zhao Y, He X
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Nature communications 2018 Apr 20;9(1):1572
Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase.
Zhang Y, Chen Z, Wang T, Yang J, Li R, Wang S, Liu J, Ye Z
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Oncotarget 2016 Jun 28;7(26):39302-39315
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Kugel S, Sebastián C, Fitamant J, Ross KN, Saha SK, Jain E, Gladden A, Arora KS, Kato Y, Rivera MN, Ramaswamy S, Sadreyev RI, Goren A, Deshpande V, Bardeesy N, Mostoslavsky R
Cell 2016 Jun 2;165(6):1401-1415
Cell 2016 Jun 2;165(6):1401-1415
Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target.
Shantha Kumara H, Kirchoff D, Caballero OL, Su T, Ahmed A, Herath SA, Njoh L, Cekic V, Simpson AJ, Cordon-Cardo C, Whelan RL
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C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis.
Wang Y, Yue D, Xiao M, Qi C, Chen Y, Sun D, Zhang N, Chen R
Journal of proteome research 2015 Feb 6;14(2):804-13
Journal of proteome research 2015 Feb 6;14(2):804-13
Role of IGF2BP3 in trophoblast cell invasion and migration.
Li W, Liu D, Chang W, Lu X, Wang YL, Wang H, Zhu C, Lin HY, Zhang Y, Zhou J, Wang H
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Cell death & disease 2014 Jan 23;5(1):e1025
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models.
Nguyen LH, Robinton DA, Seligson MT, Wu L, Li L, Rakheja D, Comerford SA, Ramezani S, Sun X, Parikh MS, Yang EH, Powers JT, Shinoda G, Shah SP, Hammer RE, Daley GQ, Zhu H
Cancer cell 2014 Aug 11;26(2):248-61
Cancer cell 2014 Aug 11;26(2):248-61
Characterization and analysis of the composition and dynamics of the mammalian riboproteome.
Reschke M, Clohessy JG, Seitzer N, Goldstein DP, Breitkopf SB, Schmolze DB, Ala U, Asara JM, Beck AH, Pandolfi PP
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Cell reports 2013 Sep 26;4(6):1276-87
The distribution of IGF2 and IMP3 in osteosarcoma and its relationship with angiogenesis.
Chen P, Wang SJ, Wang HB, Ren P, Wang XQ, Liu WG, Gu WL, Li DQ, Zhang TG, Zhou CJ
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Journal of molecular histology 2012 Feb;43(1):63-70
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 14642-1-AP(IGF2BP3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using IGF2BP3 antibody 14642-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 14642-1-AP(IGF2BP3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 14642-1-AP(IGF2BP3 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
