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- References [12]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 18977-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18977-1-AP, RRID:AB_10596482
- Product name
- IRF8 antibody
- Antibody type
- Polyclonal
- Description
- IRF8 antibody (Cat. #18977-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Knockdown of IRF8 alleviates neuroinflammation through regulating microglial activation in Parkinson's disease.
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation.
Deacetylation of IRF8 inhibits iNOS expression and inflammation via SIRT1 in macrophages.
Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.
Berberine inhibits IFN-γ signaling pathway in DSS-induced ulcerative colitis.
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
Cross-talk of pyroptosis and tumor immune landscape in lung adenocarcinoma.
Mechanism of berberine in treating Helicobacter pylori induced chronic atrophic gastritis through IRF8-IFN-γ signaling axis suppressing.
The unique regulation of implant surface nanostructure on macrophages M1 polarization.
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
IRF8 is the target of SIRT1 for the inflammation response in macrophages.
Ma L, Mi N, Wang Z, Bao R, Fang J, Ren Y, Xu X, Zhang H, Tang Y
Journal of chemical neuroanatomy 2024 Jul;138:102424
Journal of chemical neuroanatomy 2024 Jul;138:102424
TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation.
Zhao J, Li L, Feng X, Gao C, Gao L, Zhan Y, Wang Z, Zhao M, Yin H, Lu Q
Journal of autoimmunity 2023 Sep;139:103087
Journal of autoimmunity 2023 Sep;139:103087
Deacetylation of IRF8 inhibits iNOS expression and inflammation via SIRT1 in macrophages.
Jia Y, Shen K, Yang Y, Cai W, Wang K, Zhang Y, Zhao M, Luo L, Su L, Guan H, Hu D
Immunobiology 2022 Nov;227(6):152300
Immunobiology 2022 Nov;227(6):152300
Resveratrol alleviates aluminum-induced intestinal barrier dysfunction in mice.
Hao W, Zhu X, Liu Z, Song Y, Wu S, Lu X, Yang J, Jin C
Environmental toxicology 2022 Jun;37(6):1373-1381
Environmental toxicology 2022 Jun;37(6):1373-1381
Berberine inhibits IFN-γ signaling pathway in DSS-induced ulcerative colitis.
Yang T, Ma X, Wang R, Liu H, Wei S, Jing M, Li H, Zhao Y
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 Jun;30(6):764-778
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2022 Jun;30(6):764-778
Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in Helicobacter pylori-induced chronic atrophic gastritis.
Yang T, Wang R, Liu H, Wang L, Li J, Wu S, Chen X, Yang X, Zhao Y
Life sciences 2021 Feb 1;266:118903
Life sciences 2021 Feb 1;266:118903
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
Xu Y, Xu W, Liu W, Chen G, Jiang S, Chen J, Jian X, Zhang H, Liu P, Mu Y
Pharmaceutical biology 2021 Dec;59(1):1150-1160
Pharmaceutical biology 2021 Dec;59(1):1150-1160
Cross-talk of pyroptosis and tumor immune landscape in lung adenocarcinoma.
Wang X, Lin W, Liu T, Xu Z, Wang Z, Cao Z, Feng X, Gao Y, He J
Translational lung cancer research 2021 Dec;10(12):4423-4444
Translational lung cancer research 2021 Dec;10(12):4423-4444
Mechanism of berberine in treating Helicobacter pylori induced chronic atrophic gastritis through IRF8-IFN-γ signaling axis suppressing.
Yang T, Wang R, Zhang J, Bao C, Zhang J, Li R, Chen X, Wu S, Wen J, Wei S, Li H, Cai H, Yang X, Zhao Y
Life sciences 2020 May 1;248:117456
Life sciences 2020 May 1;248:117456
The unique regulation of implant surface nanostructure on macrophages M1 polarization.
He Y, Luo J, Zhang Y, Li Z, Chen F, Song W, Zhang Y
Materials science & engineering. C, Materials for biological applications 2020 Jan;106:110221
Materials science & engineering. C, Materials for biological applications 2020 Jan;106:110221
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
Sheng W, Shi X, Lin Y, Tang J, Jia C, Cao R, Sun J, Wang G, Zhou L, Dong M
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
IRF8 is the target of SIRT1 for the inflammation response in macrophages.
Jia Y, Han S, Li J, Wang H, Liu J, Li N, Yang X, Shi J, Han J, Li Y, Bai X, Su L, Hu D
Innate immunity 2017 Feb;23(2):188-195
Innate immunity 2017 Feb;23(2):188-195
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 18977-1-AP(IRF8 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IRF8 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human IRF8. This antibody recognizes human, mouse antigen. The IRF8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
