Tissue expression
Cell line expression
Protein structure
IRF8
Interferon regulatory factor 8ICSBP, ICSBP1, IRF-8
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
12 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
2 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Atlas Antibodies | ![]() |
1 references | Polyclonal |
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