Tissue expression
Cell line expression
Protein structure
IRF8
Interferon regulatory factor 8ICSBP, ICSBP1, IRF-8
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Proteintech Group | 12 references | Polyclonal |
|
||
| Invitrogen Antibodies | 2 references | Monoclonal |
|
||
| LSBio | Polyclonal |
|
|||
| Atlas Antibodies | 1 references | Polyclonal |
|
||
| Novus Biologicals | 1 references | Polyclonal |
|
||