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Protein structure
IRF8
Interferon regulatory factor 8ICSBP, ICSBP1, IRF-8
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  39-8800 |
2 references | Monoclonal |
WB
EL
FC
OA
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| Atlas Antibodies | HPA002267 |
Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NB100-1093 |
1 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN2839448 |
3 references | Polyclonal |
WB
FC
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| R&D Systems | AF5117 |
1 references | Polyclonal |
WB
IHC
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