FNab04396

antibody from FineTest Biotech

Targeting: IRF8 ICSBP, ICSBP1, IRF-8

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab04396 - Provider product page
Provider: FineTest Biotech
Product name: IRF8 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes(the interferon consensus sequence(ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes(By similarity).
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: interferon regulatory factor 8
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

IRF8 protein structure - FNab04396 shown in red.