APR02271G

IRF8 antibody from Leading Biology
ICSBP, ICSBP1, IRF-8
Western blot
Recommended by provider
Immunocytochemistry
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
APR02271G
Provider
Leading Biology
Product name
ICSBP / IRF8 Antibody (C-Terminus)
Provider product page
Leading Biology - APR02271G
Antibody type
Polyclonal
Description
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes (By similarity).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Provider Type Product Number
- No reagents -