Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1002562 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Interferon Regulatory Factor 8 (IRF8) antibody
- Antibody type
- Polyclonal
- Antigen
- Rabbit polyclol IRF8 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy-terminus of human IRF8 (GenBank accession no. NP_002154). IRF8 antibody is human, mouse, and rat reactive.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells.
Induction and regulation of IFNs during viral infections.
Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.
Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes.
Tsujimura H, Tamura T, Kong HJ, Nishiyama A, Ishii KJ, Klinman DM, Ozato K
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 1;172(11):6820-7
Journal of immunology (Baltimore, Md. : 1950) 2004 Jun 1;172(11):6820-7
Induction and regulation of IFNs during viral infections.
Malmgaard L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004 Aug;24(8):439-54
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004 Aug;24(8):439-54
Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.
Nelson N, Marks MS, Driggers PH, Ozato K
Molecular and cellular biology 1993 Jan;13(1):588-99
Molecular and cellular biology 1993 Jan;13(1):588-99
Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes.
Weisz A, Marx P, Sharf R, Appella E, Driggers PH, Ozato K, Levi BZ
The Journal of biological chemistry 1992 Dec 15;267(35):25589-96
The Journal of biological chemistry 1992 Dec 15;267(35):25589-96
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