BS6892

antibody from Bioworld Technology, Inc

Targeting: LCN2 24p3, NGAL

Immunohistochemistry

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Validation data

Product number: BS6892 - Provider product page
Provider: Bioworld Technology, Inc
Product name: LCN2 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human LCN2.
Description: Lipocalin-2, a member of the lipocalin family of proteins, was originally identified as a gelatinase-associated component of neutrophil secretory granules. Lipocalin-2 is involved in innate immunity, iron homeostasis, and apoptosis. Lipocalin-2 limits bacterial growth by binding to bacterial siderophores and sequestering iron. In mammalian cells, iron-loaded lipocalin-2 binds to its receptor, 24p3R, and is internalized, thereby releasing iron and increasing the intracellular iron concentration. Conversely, iron-free lipocalin-2 promotes apoptosis. Lipocalin-2 is also expressed in adipose tissue and promotes insulin resistance in cultured mouse adipocytes.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

LCN2 protein structure - BS6892 shown in red.