26991-1-AP

antibody from Proteintech Group

Targeting: LCN2 24p3, NGAL

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26991-1-AP

Provider

Proteintech Group

Product name

LCN2 antibody

Antibody type

Polyclonal

Description

LCN2 antibody (Cat. #26991-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation.

Li X, Dong X, Zhang L, Zhang S, Huang W, Wang C, Huo Z, Li X, Zhang X, Jia X, Chen G, Kuang B
Frontiers in pharmacology 2024;15:1285797

---

VDR Activation Attenuates Renal Tubular Epithelial Cell Ferroptosis by Regulating Nrf2/HO-1 Signaling Pathway in Diabetic Nephropathy.

Wang H, Yu X, Liu D, Qiao Y, Huo J, Pan S, Zhou L, Wang R, Feng Q, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305563

---

Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.

Pan Z, Li B, Lu P, Rong G, Wang X
Gene 2024 Feb 5;894:148026

---

mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms.

Ali Y, Gomez-Sanchez CE, Plonczynski M, Naray-Fejes-Toth A, Fejes-Toth G, Gomez-Sanchez EP
Endocrinology 2024 Feb 20;165(4)

---

Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ferroptosis-related biomarkers in alopecia areata through machine learning.

Xu W, Wei D, Song X
Scientific reports 2024 Feb 15;14(1):3800

---

Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial-mesenchymal transition.

Zhao J, Wang X, Wu Y, Zhao C
Renal failure 2024 Dec;46(1):2316259

---

Up-regulation of LCN2 in the anterior cingulate cortex contributes to neural injury-induced chronic pain.

Song XJ, Yang CL, Chen D, Yang Y, Mao Y, Cao P, Jiang A, Wang W, Zhang Z, Tao W
Frontiers in cellular neuroscience 2023;17:1140769

---

Banzhilian formula alleviates psoriasis-like lesions via the LCN2/MMP-9 axis based on transcriptome analysis.

Xing M, Yan X, Guo J, Li W, Li Z, Dong C, Guo J, Qu K, Luo Y
Frontiers in pharmacology 2023;14:1055363

---

Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.

Wang Y, He X, Xue M, Sun W, He Q, Jin J
Free radical research 2023 May-Jun;57(6-12):413-429

---

Silencing LCN2 suppresses oral squamous cell carcinoma progression by reducing EGFR signal activation and recycling.

Huang Z, Rui X, Yi C, Chen Y, Chen R, Liang Y, Wang Y, Yao W, Xu X, Huang Z
Journal of experimental & clinical cancer research : CR 2023 Mar 11;42(1):60

---

Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.

Dai L, Gao F, Wang Q, Lv X, Cheng Z, Wu Y, Chai X, Zetterberg H, Blennow K, Levey AI, Shi J, Shen Y, CANDI Consortium
Journal of neurology, neurosurgery, and psychiatry 2023 Jul;94(7):550-559

---

Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models.

Saito-Takatsuji H, Yoshitomi Y, Yamamoto R, Furuyama T, Ishigaki Y, Kato N, Yonekura H, Ikeda T
International journal of molecular sciences 2023 Feb 13;24(4)

---

Fucoxanthin Inhibits Development of Sigmoid Colorectal Cancer in a PDX Model With Alterations of Growth, Adhesion, and Cell Cycle Signals.

Terasaki M, Tsuruoka K, Tanaka T, Maeda H, Shibata M, Miyashita K, Kanemitsu Y, Sekine S, Takahashi M, Yagishita S, Hamada A
Cancer genomics & proteomics 2023 Dec;20(6suppl):686-705

---

Increasing expression of STING by ERα antagonizes LCN2 downregulation during chronic endometritis.

Chu M, He S, Zhao H, Yin S, Liu Z, Zhang W, Liu X, Bao H
Journal of reproductive immunology 2023 Dec;160:104167

---

Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.

Tong L, Rao J, Yang C, Xu J, Lu Y, Zhang Y, Cang X, Xie S, Mao J, Jiang P
iScience 2023 Aug 18;26(8):107446

---

IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2.

Lan Y, Yang T, Yue Q, Wang Z, Zhong X, Luo X, Zuo B, Zhang M, Zeng T, Liu B, Guo H
iScience 2023 Aug 18;26(8):107377

---

Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation.

Zhao S, Huang Z, Jiang H, Xiu J, Zhang L, Long Q, Yang Y, Yu L, Lu L, Gu H
Oxidative medicine and cellular longevity 2022;2022:1671438

---

Intermittent hilar occlusion attenuates or prevents renal ischaemia-reperfusion in mice.

Wang L, Peng C, Chen J, Li H, Jiao Q, Zhang Z, Wang L, Yuan Q, Wang B, Huang Y, Ma X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113457

---

Single-cell transcriptomic analysis highlights origin and pathological process of human endometrioid endometrial carcinoma.

Ren X, Liang J, Zhang Y, Jiang N, Xu Y, Qiu M, Wang Y, Zhao B, Chen X
Nature communications 2022 Oct 22;13(1):6300

---

Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.

Hou Y, Wang S, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Yang G
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223

---

PLK2 targets GSK3β to protect against cisplatin-induced acute kidney injury.

Wei X, Wu J, Li J, Yang Q
Experimental cell research 2022 Aug 1;417(1):113181

---

miR-132-3p promotes the cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells by targeting SIRT1 via the NF-κB pathway.

Han S, Lin F, Ruan Y, Zhao S, Yuan R, Ning J, Jiang K, Xie J, Li H, Li C, Rao T, Yu W, Xia Y, Zhou X, Cheng F
International immunopharmacology 2021 Oct;99:108022

---

Ranolazine alleviates contrast-associated acute kidney injury through modulation of calcium independent oxidative stress and apoptosis.

Ma C, Chen T, Ti Y, Yang Y, Qi Y, Zhang C, Liu L, Bu P
Life sciences 2021 Feb 15;267:118920

---

Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice.

Qian CL, Ding CL, Tang HL, Qi ZT, Wang W
Cell biochemistry and function 2020 Aug;38(6):753-760

---

TET2 is involved in DNA hydroxymethylation, cell proliferation and inflammatory response in keratinocytes.

Liu X, Wang X, Liu N, Zhu K, Zhang S, Duan X, Huang Y, Jin Z, Jaypaul H, Wu Y, Chen H
Molecular medicine reports 2020 Apr;21(4):1941-1949