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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA002695 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA002695, RRID:AB_1852758
- Product name
- Anti-LCN2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human LCN2, Gene description: lipocalin 2, Alternative Gene Names: 24p3, NGAL, Validated applications: WB, IHC, Uniprot ID: P80188, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn’s disease
Osteoblast‐derived extracellular vesicles exert osteoblastic and tumor‐suppressive functions via SERPINA3 and LCN2 in prostate cancer
Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression
Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma
Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses
Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer
Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?
Lipocalin 2 Plays an Immunomodulatory Role and Has Detrimental Effects after Spinal Cord Injury
Li J, Simmons A, Hawkins C, Chiron S, Ramirez-Solano M, Tasneem N, Kaur H, Xu Y, Revetta F, Vega P, Bao S, Cui C, Tyree R, Raber L, Conner A, Pilat J, Jacobse J, McNamara K, Allaman M, Raffa G, Gobert A, Asim M, Goettel J, Choksi Y, Beaulieu D, Dalal R, Horst S, Pabla B, Huo Y, Landman B, Roland J, Scoville E, Schwartz D, Washington M, Shyr Y, Wilson K, Coburn L, Lau K, Liu Q
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Osteoblast‐derived extracellular vesicles exert osteoblastic and tumor‐suppressive functions via SERPINA3 and LCN2 in prostate cancer
Ito K, Yamamoto T, Hayashi Y, Sato S, Nakayama J, Urabe F, Shimasaki T, Nakamura E, Matui Y, Fujimoto H, Kimura T, Egawa S, Ochiya T, Yamamoto Y
Molecular Oncology 2023;17(10):2147-2167
Molecular Oncology 2023;17(10):2147-2167
Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression
Støy S, Laursen T, Glavind E, Eriksen P, Terczynska-Dyla E, Magnusson N, Hamilton-Dutoit S, Mortensen F, Veidal S, Rigbolt K, Riggio O, Deleuran B, Vilstrup H, Sandahl T
Clinical and Translational Gastroenterology 2020;11(8):e00197
Clinical and Translational Gastroenterology 2020;11(8):e00197
Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma
Molina L, Bell D, Tao J, Preziosi M, Pradhan-Sundd T, Singh S, Poddar M, Luo J, Ranganathan S, Chikina M, Monga S
The American Journal of Pathology 2018;188(8):1895-1909
The American Journal of Pathology 2018;188(8):1895-1909
Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses
Murtha M, Eichler T, Bender K, Metheny J, Li B, Schwaderer A, Mosquera C, James C, Schwartz L, Becknell B, Spencer J
Journal of Clinical Investigation 2018;128(12):5634-5646
Journal of Clinical Investigation 2018;128(12):5634-5646
Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer
Candido S, Maestro R, Polesel J, Catania A, Maira F, Signorelli S, McCubrey J, Libra M
Oncotarget 2014;5(6):1576-1594
Oncotarget 2014;5(6):1576-1594
Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?
McLean M, Thomson A, Murray G, Fyfe N, Hold G, El-Omar E
British Journal of Cancer 2013;108(12):2537-2541
British Journal of Cancer 2013;108(12):2537-2541
Lipocalin 2 Plays an Immunomodulatory Role and Has Detrimental Effects after Spinal Cord Injury
Rathore K, Berard J, Redensek A, Chierzi S, Lopez-Vales R, Santos M, Akira S, David S
The Journal of Neuroscience 2011;31(38):13412-13419
The Journal of Neuroscience 2011;31(38):13412-13419
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in Capan-2 cells transfected with control siRNA, target specific siRNA probe #1, using Anti-LCN2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human bone marrow and testis tissues using HPA002695 antibody. Corresponding LCN2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
