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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 609706 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#609706, RRID:AB_2563124
- Product name
- PE anti-SSRP1
- Antibody type
- Monoclonal
- Antigen
- Recombinant (partial) (308-524aa)
- Description
- SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Yellow dye
- Antibody clone number
- 10D1
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were treated with Nuclear Factor Fixation and Permeabilization Buffer Set (Cat# 422601) and then stained with anti-SSRP-1 (clone 10D1) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).
- Conjugate
- Yellow dye
