Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 609708 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#609708, RRID:AB_2566464
- Product name
- Alexa Fluor® 647 anti-SSRP1
- Antibody type
- Monoclonal
- Antigen
- Recombinant (partial) (308-524aa)
- Description
- SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D1 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Red dye
- Antibody clone number
- 10D1
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were treated with True-Nuclear™ Transcription Factor Buffer Set and then stained with anti-SSRP-1 (clone 10D1) Alexa Fluor® 647 (filled histogram) or mouse IgG2b, κ Alexa Fluor® 647 isotype control (open histogram).
- Conjugate
- Red dye