WRN

gene product
RECQ3, RECQL2
This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [provided by RefSeq, Jul 2008]
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278 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
91 antibodies
Novus Biologicals
25 antibodies
GeneTex
2 antibodies
Abnova Corporation
3 antibodies
Affinity Biosciences
1 antibody
Invitrogen Antibodies
4 antibodies
Antibodies Incorporated
2 antibodies
Abgent
2 antibodies
Biorbyt
5 antibodies
OriGene
2 antibodies
Acris Antibodies GmbH
2 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
41 antibodies
Cell Signaling Technology, Inc
1 antibody
Bethyl Laboratories
3 antibodies
NovoPro Bioscience Inc.
1 antibody
RabMAbs
6 antibodies
Aviva Systems Biology
2 antibodies
Proteintech Group
1 antibody
Creative Biolabs
19 antibodies
NSJ Bioreagents
1 antibody
ProSci
1 antibody
United States Biological
39 antibodies
Creative Diagnostics
5 antibodies
Sigma-Aldrich
4 antibodies
St John's Laboratory
2 antibodies
Abiocode, Inc.
1 antibody
Active Motif
1 antibody
Boster Biological Technology
1 antibody
RayBiotech, Inc.
1 antibody
MyBioSource
2 antibodies
Abbiotec
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
GenWay
1 antibody
UC Davis/NIH NeuroMab Facility
2 antibodies
EMD Millipore
1 antibody