ABIN318945

antibody from antibodies-online

Targeting: WRN RECQ3, RECQL2

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ABIN318945

Provider

antibodies-online

Product name

anti-RECQL2 (ARABIDOPSIS RECQ HELICASE L2), 3'-5' DNA Helicase/ ATP-Dependent Helicase/ Four-Way Junction Helicase/ Protein Binding (RECQL2) (AA 1400-1432) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to an epitope within amino acid residues 1400-1432 of human WRN

Description

Purified

Reactivity

Human

Host

Rabbit

Epitope

AA 1400-1432

Isotype

IgG

Vial size

50 μg

Concentration

1.0mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

The spectrum of WRN mutations in Werner syndrome patients.

Huang S, Lee L, Hanson NB, Lenaerts C, Hoehn H, Poot M, Rubin CD, Chen DF, Yang CC, Juch H, Dorn T, Spiegel R, Oral EA, Abid M, Battisti C, Lucci-Cordisco E, Neri G, Steed EH, Kidd A, Isley W, Showalter D, Vittone JL, Konstantinow A, Ring J, Meyer P, Wenger SL, von Herbay A, Wollina U, Schuelke M, Huizenga CR, Leistritz DF, Martin GM, Mian IS, Oshima J
Human mutation 2006 Jun;27(6):558-67

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Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.

Li B, Comai L
The Journal of biological chemistry 2001 Mar 30;276(13):9896-902