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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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- Product number
- ABIN955584 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-RECQL2 (ARABIDOPSIS RECQ HELICASE L2), 3'-5' DNA Helicase/ ATP-Dependent Helicase/ Four-Way Junction Helicase/ Protein Binding (RECQL2) (Middle Region), (AA 794-825), (Thr802) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide between 794-825 (T802 amino acids from the Central region of human WRN
- Description
- Protein A column; followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Middle Region,AA 794-825,Thr802
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store at 2 - 8°C for up to six months or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
WRN participates in translesion synthesis pathway through interaction with NBS1.
Variation within DNA repair pathway genes and risk of multiple sclerosis.
An association study of SERPING1 gene and age-related macular degeneration in a Han Chinese population.
Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
WRN participates in translesion synthesis pathway through interaction with NBS1.
Kobayashi J, Okui M, Asaithamby A, Burma S, Chen BP, Tanimoto K, Matsuura S, Komatsu K, Chen DJ
Mechanisms of ageing and development 2010 Jun;131(6):436-44
Mechanisms of ageing and development 2010 Jun;131(6):436-44
Variation within DNA repair pathway genes and risk of multiple sclerosis.
Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, International Multiple Sclerosis Genetics Consortium
American journal of epidemiology 2010 Jul 15;172(2):217-24
American journal of epidemiology 2010 Jul 15;172(2):217-24
An association study of SERPING1 gene and age-related macular degeneration in a Han Chinese population.
Lu F, Zhao P, Fan Y, Tang S, Hu J, Liu X, Yang X, Chen Y, Li T, Lei C, Yang J, Lin Y, Ma S, Li C, Shi Y, Yang Z
Molecular vision 2010 Jan 10;16:1-6
Molecular vision 2010 Jan 10;16:1-6
Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.
Perry JJ, Asaithamby A, Barnebey A, Kiamanesch F, Chen DJ, Han S, Tainer JA, Yannone SM
The Journal of biological chemistry 2010 Aug 13;285(33):25699-707
The Journal of biological chemistry 2010 Aug 13;285(33):25699-707
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WRN Antibody (Center T802) (AP54571PU-N) western blot analysis in K562 cell line lysates (35 μg/lane). This demonstrates the WRN antibody detected the WRN protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WRN Antibody (Center T802) (AP54571PU-N) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
