Tissue expression
Cell line expression
Protein structure
MCM3AP
Minichromosome maintenance complex component 3 associated proteinGANP, KIAA0572, Map80, SAC3
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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Proteintech Group | 11054-1-AP | 4 references | Polyclonal |
WB
EL
ICC
IP
IHC
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Invitrogen Antibodies | 11054-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
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NovoPro Bioscience Inc. | 110862 | Polyclonal |
WB
EL
ICC
IP
IHC
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FineTest Biotech | FNab03340 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Atlas Antibodies | HPA021527 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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