Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17354-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- MKNK2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MKNK2 antibody (Cat. #17354-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hsa_circ_0000313/miR-1224-3p/MKNK2 Axis Modulates CD4(+) T Cells by Activating p38 MAPK Signaling in Myasthenia Gravis.
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
High Expression of miR-6785-5p in the Serum Exosomes of Psoriasis Patients Alleviates Psoriasis-Like Skin Damage by Interfering with the MNK2/p-eIF4E Axis in Keratinocytes.
Non-Sugar Sweetener Rubusoside Alleviates Lipid Metabolism Disorder In Vivo and In Vitro by Targeting PPARγ/α, Lgals3, and Mknk2.
Inhibitory effects of Tomivosertib in acute myeloid leukemia.
Down-regulation of the insulin signaling pathway by SHC may correlate with congenital heart disease in Chinese populations.
Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma.
Li Y, Kong X, Cai H, Tian W, Ren Y, Xu F, Peng S, Niu J, Xin G, Wang J, Zhang H, Wang L
Mediators of inflammation 2026;2026(1):e2877539
Mediators of inflammation 2026;2026(1):e2877539
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
Gao Y, Zhu J, Xin H, Ni B, Liu Z
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
High Expression of miR-6785-5p in the Serum Exosomes of Psoriasis Patients Alleviates Psoriasis-Like Skin Damage by Interfering with the MNK2/p-eIF4E Axis in Keratinocytes.
Wang R, Huang Y, Shao K, Yan J, Sun Q
Inflammation 2024 Oct;47(5):1585-1599
Inflammation 2024 Oct;47(5):1585-1599
Non-Sugar Sweetener Rubusoside Alleviates Lipid Metabolism Disorder In Vivo and In Vitro by Targeting PPARγ/α, Lgals3, and Mknk2.
Huang W, Jiang M, Wang X, Pan D, Chen W, Fan L
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25601-25619
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25601-25619
Inhibitory effects of Tomivosertib in acute myeloid leukemia.
Suarez M, Blyth GT, Mina AA, Kosciuczuk EM, Dolniak B, Dinner S, Altman JK, Eklund EA, Saleiro D, Beauchamp EM, Platanias LC
Oncotarget 2021 May 11;12(10):955-966
Oncotarget 2021 May 11;12(10):955-966
Down-regulation of the insulin signaling pathway by SHC may correlate with congenital heart disease in Chinese populations.
Luo Z, Xu L, Lu J, Shen Y, Tang Y, Wang X, Wu Y, Sun H, Guo T
Clinical science (London, England : 1979) 2020 Feb 14;134(3):349-358
Clinical science (London, England : 1979) 2020 Feb 14;134(3):349-358
Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma.
Ichiyanagi O, Ito H, Naito S, Kabasawa T, Kanno H, Narisawa T, Ushijima M, Kurota Y, Ozawa M, Sakurai T, Nishida H, Kato T, Yamakawa M, Tsuchiya N
Oncotarget 2019 Jun 18;10(40):4053-4068
Oncotarget 2019 Jun 18;10(40):4053-4068
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 17354-1-AP( MKNK2 Antibody) at dilution of 1:300
- Validation comment
- WB