SEC14L2

This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]

Description

SEC14 like lipid binding 2

Tissue specificity

Tissue enhanced (epididymis, liver)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

22:q12.2 (30396941 - 30425303)

Ensembl ID

ENSG00000100003  (ver. 103.38)

Orthologs

-

UniProt

O76054

neXtProt

NX_O76054

Human splice variants