IC6472P

antibody from Novus Biologicals

Targeting: BIRC5 API4, EPR-1, survivin

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

IC6472P

Provider

Novus Biologicals

Product name

Mouse Monoclonal Survivin Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Survivin in direct ELISAs.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

100 Tests

Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.

References

Submitted references

Survivin-specific T cell receptor targets tumor but not T cells.

Arber C, Feng X, Abhyankar H, Romero E, Wu MF, Heslop HE, Barth P, Dotti G, Savoldo B
The Journal of clinical investigation 2015 Jan;125(1):157-68

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Activation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritis.

Andersson SE, Svensson MN, Erlandsson MC, Dehlin M, Andersson KM, Bokarewa MI
PloS one 2012;7(10):e47668

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Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern.

Mera S, Magnusson M, Tarkowski A, Bokarewa M
Journal of leukocyte biology 2008 Jan;83(1):149-55

Flow cytometry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Detection of Survivin in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human Survivin PE-conjugated Monoclonal Antibody (Catalog # IC6472P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.