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Protein structure
BIRC5
Baculoviral IAP repeat containing 5API4, EPR-1, survivin
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Top validated antibodies |
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| Novus Biologicals |  NB500-201 |
347 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
ChIP
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| Invitrogen Antibodies | PA1-16836 |
8 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
ChIP
OA
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| Proteintech Group | 10508-1-AP |
145 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| antibodies-online | ABIN446306 |
290 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
ChIP
|
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| LSBio | LS-C169452 |
Monoclonal |
WB
EL
ICC
IHC
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