M00379-1

antibody from Boster Biological Technology
Targeting: BIRC5 API4, EPR-1, survivin
Provider product page for M00379-1
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
M00379-1 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-Survivin BIRC5 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for Survivin/BIRC5 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, IF, IHC, ICC, WB. Reactive species: Human Survivin/BIRC5 information: Molecular Weight: 16389 MW; Subcellular Localization: Cytoplasm. Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Midbody. Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody. Colocalizes with AURKB at mitotic chromosomes. Acetylation at Lys-129 directs its localization to the nucleus by enhancing homodimerization and thereby inhibiting XPO1/CRM1- mediated nuclear export; Tissue Specificity: Expressed only in fetal kidney and liver, and to lesser extent, lung and brain. Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas. Also expressed in various renal cell carcinoma cell lines.
Reactivity
Human
Host
Rabbit
Antibody clone number
ABB-2
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
BIRC5 protein structure - M00379-1 shown in red.