CABT-L682

antibody from Creative Diagnostics
Targeting: BIRC5 API4, EPR-1, survivin
Provider product page for CABT-L682
Western blot
Immunohistochemistry

Antibody data

Product number
CABT-L682 - Provider product page
Provider
Creative Diagnostics
Product name
Rabbit Anti-ADRBK1 monoclonal antibody, clone TU16-71
Antibody type
Monoclonal
Description
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonist-mediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first class is comprised of the second messenger-regulated kinases, such as c-AMP dependent protein kinase A and protein kinase C. The second class includes the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1), two forms of beta-adrenergic receptor kinase: GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
TU16-71
Vial size
100 _l
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
BIRC5 protein structure - CABT-L682 shown in red.