Explore
Validate
Learn
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN269272 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Survivin (BIRC5) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 8E2
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Survivin expression impacts prognostically on NSCLC but not SCLC.
Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis.
Megakaryocytes express functional Aurora-B kinase in endomitosis.
Regulation of survivin function by Hsp90.
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells.
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.
Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia.
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.
Expression of survivin correlates with apoptosis, proliferation, and angiogenesis during human colorectal tumorigenesis.
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin.
Expression of survivin and its relationship to loss of apoptosis in breast carcinomas.
Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma.
Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer.
Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.
Control of apoptosis and mitotic spindle checkpoint by survivin.
Rosato A, Menin C, Boldrin D, Dalla Santa S, Bonaldi L, Scaini MC, Del Bianco P, Zardo D, Fassan M, Cappellesso R, Fassina A
Lung cancer (Amsterdam, Netherlands) 2013 Feb;79(2):180-6
Lung cancer (Amsterdam, Netherlands) 2013 Feb;79(2):180-6
Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis.
Zeng SX, Li Y, Jin Y, Zhang Q, Keller DM, McQuaw CM, Barklis E, Stone S, Hoatlin M, Zhao Y, Lu H
Molecular and cellular biology 2010 Feb;30(4):935-47
Molecular and cellular biology 2010 Feb;30(4):935-47
Megakaryocytes express functional Aurora-B kinase in endomitosis.
Geddis AE, Kaushansky K
Blood 2004 Aug 15;104(4):1017-24
Blood 2004 Aug 15;104(4):1017-24
Regulation of survivin function by Hsp90.
Fortugno P, Beltrami E, Plescia J, Fontana J, Pradhan D, Marchisio PC, Sessa WC, Altieri DC
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):13791-6
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):13791-6
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells.
Carvalho A, Carmena M, Sambade C, Earnshaw WC, Wheatley SP
Journal of cell science 2003 Jul 15;116(Pt 14):2987-98
Journal of cell science 2003 Jul 15;116(Pt 14):2987-98
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.
Fortugno P, Wall NR, Giodini A, O'Connor DS, Plescia J, Padgett KM, Tognin S, Marchisio PC, Altieri DC
Journal of cell science 2002 Feb 1;115(Pt 3):575-85
Journal of cell science 2002 Feb 1;115(Pt 3):575-85
Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia.
Granziero L, Ghia P, Circosta P, Gottardi D, Strola G, Geuna M, Montagna L, Piccoli P, Chilosi M, Caligaris-Cappio F
Blood 2001 May 1;97(9):2777-83
Blood 2001 May 1;97(9):2777-83
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.
Wheatley SP, Carvalho A, Vagnarelli P, Earnshaw WC
Current biology : CB 2001 Jun 5;11(11):886-90
Current biology : CB 2001 Jun 5;11(11):886-90
Expression of survivin correlates with apoptosis, proliferation, and angiogenesis during human colorectal tumorigenesis.
Kawasaki H, Toyoda M, Shinohara H, Okuda J, Watanabe I, Yamamoto T, Tanaka K, Tenjo T, Tanigawa N
Cancer 2001 Jun 1;91(11):2026-32
Cancer 2001 Jun 1;91(11):2026-32
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin.
O'Connor DS, Grossman D, Plescia J, Li F, Zhang H, Villa A, Tognin S, Marchisio PC, Altieri DC
Proceedings of the National Academy of Sciences of the United States of America 2000 Nov 21;97(24):13103-7
Proceedings of the National Academy of Sciences of the United States of America 2000 Nov 21;97(24):13103-7
Expression of survivin and its relationship to loss of apoptosis in breast carcinomas.
Tanaka K, Iwamoto S, Gon G, Nohara T, Iwamoto M, Tanigawa N
Clinical cancer research : an official journal of the American Association for Cancer Research 2000 Jan;6(1):127-34
Clinical cancer research : an official journal of the American Association for Cancer Research 2000 Jan;6(1):127-34
Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma.
Grossman D, McNiff JM, Li F, Altieri DC
The Journal of investigative dermatology 1999 Dec;113(6):1076-81
The Journal of investigative dermatology 1999 Dec;113(6):1076-81
Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer.
Kawasaki H, Altieri DC, Lu CD, Toyoda M, Tenjo T, Tanigawa N
Cancer research 1998 Nov 15;58(22):5071-4
Cancer research 1998 Nov 15;58(22):5071-4
Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.
Lu CD, Altieri DC, Tanigawa N
Cancer research 1998 May 1;58(9):1808-12
Cancer research 1998 May 1;58(9):1808-12
Control of apoptosis and mitotic spindle checkpoint by survivin.
Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, Altieri DC
Nature 1998 Dec 10;396(6711):580-4
Nature 1998 Dec 10;396(6711):580-4
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ICC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
