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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- NB500-237 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB500-237, RRID:AB_10001712
- Product name
- Mouse Monoclonal Survivin Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. Survivin Antibody (32.1) [NB500-237] is specific for the nuclear form of survivin.
- Reactivity
- Human, Hamster
- Host
- Mouse
- Antigen sequence
The epitope recognized is between a
mino acids 3-19- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.9 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references From stem cells protection to skin microbiota balance: Orobanche rapum extract, a new natural strategy.
Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy.
The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex.
The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells.
The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro.
Intracellular localization of survivin determines biological behavior in colorectal cancer.
Intracellular localization of survivin determines biological behavior in colorectal cancer.
The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney.
Nuclear expression of the antiapoptotic protein survivin in malignant melanoma.
Regulation of microtubule stability and mitotic progression by survivin.
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.
Meunier M, Scandolera A, Chapuis E, Lambert C, Jarrin C, Robe P, Chajra H, Auriol D, Reynaud R
Journal of cosmetic dermatology 2019 Aug;18(4):1140-1154
Journal of cosmetic dermatology 2019 Aug;18(4):1140-1154
Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy.
Wu X, Li Y, Liu X, Chen C, Harrington SM, Cao S, Xie T, Pham T, Mansfield AS, Yan Y, Kwon ED, Wang L, Ling K, Dong H
Heliyon 2018 Dec;4(12):e01039
Heliyon 2018 Dec;4(12):e01039
The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.
Hori M, Miki T, Okamoto M, Yazama F, Konishi H, Kaneko H, Shimamoto F, Ota T, Temme A, Tatsuka M
PloS one 2013;8(2):e55710
PloS one 2013;8(2):e55710
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex.
Guvenc H, Pavlyukov MS, Joshi K, Kurt H, Banasavadi-Siddegowda YK, Mao P, Hong C, Yamada R, Kwon CH, Bhasin D, Chettiar S, Kitange G, Park IH, Sarkaria JN, Li C, Shakhparonov MI, Nakano I
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Feb 1;19(3):631-42
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Feb 1;19(3):631-42
The oncofetal gene survivin promotes cell proliferation and survival in primary human osteoblastic cells.
Lechler P, Schaumburger J, Köck FX, Balakrishnan S, Doukas S, Prantl L, Grifka J
Calcified tissue international 2011 Sep;89(3):211-20
Calcified tissue international 2011 Sep;89(3):211-20
The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro.
Lechler P, Renkawitz T, Campean V, Balakrishnan S, Tingart M, Grifka J, Schaumburger J
BMC cancer 2011 Apr 2;11:120
BMC cancer 2011 Apr 2;11:120
Intracellular localization of survivin determines biological behavior in colorectal cancer.
Qi G, Tuncel H, Aoki E, Tanaka S, Oka S, Kaneko I, Okamoto M, Tatsuka M, Nakai S, Shimamoto F
Oncology reports 2009 Sep;22(3):557-62
Oncology reports 2009 Sep;22(3):557-62
Intracellular localization of survivin determines biological behavior in colorectal cancer.
Qi G, Tuncel H, Aoki E, Tanaka S, Oka S, Kaneko I, Okamoto M, Tatsuka M, Nakai S, Shimamoto F
Oncology reports 2009 Sep;22(3):557-62
Oncology reports 2009 Sep;22(3):557-62
The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney.
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, Klanke B, Weidemann A, Warnecke C, Amann K, Engehausen D, Willam C, Eckardt KU, Rödel F, Wiesener MS
The American journal of pathology 2007 Nov;171(5):1483-98
The American journal of pathology 2007 Nov;171(5):1483-98
Nuclear expression of the antiapoptotic protein survivin in malignant melanoma.
Ding Y, Prieto VG, Zhang PS, Rosenthal S, Smith KJ, Skelton HG, Diwan AH
Cancer 2006 Mar 1;106(5):1123-9
Cancer 2006 Mar 1;106(5):1123-9
Regulation of microtubule stability and mitotic progression by survivin.
Giodini A, Kallio MJ, Wall NR, Gorbsky GJ, Tognin S, Marchisio PC, Symons M, Altieri DC
Cancer research 2002 May 1;62(9):2462-7
Cancer research 2002 May 1;62(9):2462-7
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.
Fortugno P, Wall NR, Giodini A, O'Connor DS, Plescia J, Padgett KM, Tognin S, Marchisio PC, Altieri DC
Journal of cell science 2002 Feb 1;115(Pt 3):575-85
Journal of cell science 2002 Feb 1;115(Pt 3):575-85
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Survivin Antibody (32.1) [NB500-237] - Immunohistochemical staining of formalin-fixed paraffin-embedded human lung cancer tissue using Survivin Antibody (32.1) [NB500-237].
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: Survivin Antibody (32.1) [NB500-237] - An intracellular stain was performed on HeLa cells with FITC-conjugated Survivin Antibody (32.1) [NB500-237F] (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 10 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to FITC.
