Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NB100-56167 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56167, RRID:AB_838942
- Product name
- Rabbit Polyclonal Survivin Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Activation of IGF-1R pathway and NPM-ALK G1269A mutation confer resistance to crizotinib treatment in NPM-ALK positive lymphoma.
YM155 Reverses Statin Resistance in Renal Cancer by Reducing Expression of Survivin.
YM155 reverses rapamycin resistance in renal cancer by decreasing survivin.
Survivin is associated with cell proliferation and has a role in 1a,25-dihydroxyvitamin D3 induced cell growth inhibition in prostate cancer.
Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain.
Li Y, Wang K, Song N, Hou K, Che X, Zhou Y, Liu Y, Zhang J
Investigational new drugs 2020 Jun;38(3):599-609
Investigational new drugs 2020 Jun;38(3):599-609
YM155 Reverses Statin Resistance in Renal Cancer by Reducing Expression of Survivin.
Nitta T, Koike H, Miyao T, Miyazawa Y, Kato H, Furuya Y, Sekine Y, Suzuki K
Anticancer research 2017 Jan;37(1):75-80
Anticancer research 2017 Jan;37(1):75-80
YM155 reverses rapamycin resistance in renal cancer by decreasing survivin.
Koike H, Nitta T, Sekine Y, Arai S, Furuya Y, Nomura M, Matsui H, Shibata Y, Ito K, Oyama T, Suzuki K
Journal of cancer research and clinical oncology 2014 Oct;140(10):1705-13
Journal of cancer research and clinical oncology 2014 Oct;140(10):1705-13
Survivin is associated with cell proliferation and has a role in 1a,25-dihydroxyvitamin D3 induced cell growth inhibition in prostate cancer.
Koike H, Morikawa Y, Sekine Y, Matsui H, Shibata Y, Suzuki K
The Journal of urology 2011 Apr;185(4):1497-503
The Journal of urology 2011 Apr;185(4):1497-503
Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain.
Villapol S, Acarin L, Faiz M, Castellano B, Gonzalez B
Neuroscience 2008 Apr 22;153(1):108-19
Neuroscience 2008 Apr 22;153(1):108-19
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Survivin Antibody [NB100-56167] - Analysis of Survivin using [NB100-56167]. Survivin was detected in the two tumor cell lines, Jurkat (T cell lymphoma) and RS11846 (non-Hodgkin's lymphoma), but not in lysates from normal tissues. Survivin RP, full-length recombinant human survivin protein was used as a positive control. Bands observed slightly lower than the theoretical molecular weight, 16 kDa.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Survivin Antibody [NB100-56167] - Immunohistochemical analysis of Survivin in formalin-fixed paraffin-embedded human prostate and breast cancer using Survivin Antibody [NB100-56167]. A and A1, prostate cancer at low and high magnification, respectively. B and B1, breast cancer. B1 is a high magnification of an area of metastasis. Hematoxylin-eosin counterstain.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Survivin Antibody [NB100-56167] - Analysis of Survivin in a formalin-fixed paraffin-embedded human brain tissue microarray using Survivin Antibody [NB100-56167]. A. Differential expression of Survivin in brain tumors from six different patients. A1-A3, high magnification from A. A1, gemistocytic astrocytoma. A2, medulloblastoma. A3, choroid plexus papilloma. Hematoxylin-eosin counterstain.