Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- NB500-236 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB500-236, RRID:AB_10081301
- Product name
- Rabbit Polyclonal Survivin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Survivin [p Thr34] Antibody [NB500-236] is specific for phosphorylated survivin.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references A direct interaction between survivin and myosin II is required for cytokinesis.
Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.
PIN1 inhibits apoptosis in hepatocellular carcinoma through modulation of the antiapoptotic function of survivin.
Spongiatriol inhibits nuclear factor kappa B activation and induces apoptosis in pancreatic cancer cells.
Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation.
Targeting the 90 kDa heat shock protein improves photodynamic therapy.
3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin.
Survivin, a member of the inhibitor of apoptosis family, is induced by photodynamic therapy and is a target for improving treatment response.
Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells.
Babkoff A, Cohen-Kfir E, Aharon H, Ronen D, Rosenberg M, Wiener R, Ravid S
Journal of cell science 2019 Jul 17;132(14)
Journal of cell science 2019 Jul 17;132(14)
Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.
Eiteneuer A, Seiler J, Weith M, Beullens M, Lesage B, Krenn V, Musacchio A, Bollen M, Meyer H
The EMBO journal 2014 Nov 18;33(22):2704-20
The EMBO journal 2014 Nov 18;33(22):2704-20
PIN1 inhibits apoptosis in hepatocellular carcinoma through modulation of the antiapoptotic function of survivin.
Cheng CW, Chow AK, Pang R, Fok EW, Kwong YL, Tse E
The American journal of pathology 2013 Mar;182(3):765-75
The American journal of pathology 2013 Mar;182(3):765-75
Spongiatriol inhibits nuclear factor kappa B activation and induces apoptosis in pancreatic cancer cells.
Guzmán E, Maher M, Temkin A, Pitts T, Wright A
Marine drugs 2013 Apr 2;11(4):1140-51
Marine drugs 2013 Apr 2;11(4):1140-51
Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation.
AbouAlaiwi WA, Ratnam S, Booth RL, Shah JV, Nauli SM
Human molecular genetics 2011 Jan 15;20(2):354-67
Human molecular genetics 2011 Jan 15;20(2):354-67
Targeting the 90 kDa heat shock protein improves photodynamic therapy.
Ferrario A, Gomer CJ
Cancer letters 2010 Mar 28;289(2):188-94
Cancer letters 2010 Mar 28;289(2):188-94
3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin.
Bhatnagar N, Li X, Chen Y, Zhou X, Garrett SH, Guo B
Cancer prevention research (Philadelphia, Pa.) 2009 Jun;2(6):581-9
Cancer prevention research (Philadelphia, Pa.) 2009 Jun;2(6):581-9
Survivin, a member of the inhibitor of apoptosis family, is induced by photodynamic therapy and is a target for improving treatment response.
Ferrario A, Rucker N, Wong S, Luna M, Gomer CJ
Cancer research 2007 May 15;67(10):4989-95
Cancer research 2007 May 15;67(10):4989-95
Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells.
Liu T, Brouha B, Grossman D
Oncogene 2004 Jan 8;23(1):39-48
Oncogene 2004 Jan 8;23(1):39-48
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Survivin [p Thr34] Antibody [NB500-236] - Western blot analysis using [NB500-236]. Lane 1: Phosphorylated Survivin protein and Lane 2: Non-phosphorylated Survivin protein. Note: theoretical molecular weight of Survivin Antibody: 16 kDa.