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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Immunohistochemistry [1]
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- Product number
- M00048 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for Caspase 1/CASP1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC, WB. Reactive species: Human, Rat Caspase 1/CASP1 information: Molecular Weight: 45159 MW; Subcellular Localization: Cytoplasm; Tissue Specificity: Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Antibody clone number
- DCB-3
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Hsa_circ_0008833 promotes COPD progression via inducing pyroptosis in bronchial epithelial cells.
A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury.
Edaravone dexborneol alleviates cerebral ischemia-reperfusion injury through NF-κB/NLRP3 signal pathway.
Involvement of the heat shock response (HSR) regulatory pathway in cadmium-elicited cerebral damage.
lncRNA GAS5 promotes pyroptosis in COPD by functioning as a ceRNA to regulate the miR‑223‑3p/NLRP3 axis.
Azeliragon ameliorates Alzheimer's disease via the Janus tyrosine kinase and signal transducer and activator of transcription signaling pathway.
Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission.
Programmed death-ligand 1 triggers PASMCs pyroptosis and pulmonary vascular fibrosis in pulmonary hypertension.
Pre-administration of luteoline attenuates neonatal sevoflurane-induced neurotoxicity in mice.
Vector Analysis of Cytoskeletal Structural Tension and the Mechanisms that Underpin Spectrin-Related Forces in Pyroptosis.
Role of NLRP3 Inflammasome in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis with Nasal Polyps.
Xie T, Yang Z, Xian S, Lin Q, Huang L, Ding Y
Experimental lung research 2024;50(1):1-14
Experimental lung research 2024;50(1):1-14
A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury.
Xie L, Wu H, He Q, Shi W, Zhang J, Xiao X, Yu T
Cell communication and signaling : CCS 2024 Jan 12;22(1):33
Cell communication and signaling : CCS 2024 Jan 12;22(1):33
Edaravone dexborneol alleviates cerebral ischemia-reperfusion injury through NF-κB/NLRP3 signal pathway.
Shen G, Lou C, Li Q, Zhao B, Luo Y, Wu F, Jiao D, Fang M, Geng Y
Anatomical record (Hoboken, N.J. : 2007) 2024 Feb;307(2):372-384
Anatomical record (Hoboken, N.J. : 2007) 2024 Feb;307(2):372-384
Involvement of the heat shock response (HSR) regulatory pathway in cadmium-elicited cerebral damage.
Talukder M, Bi SS, Lv MW, Ge J, Zhang C, Li JL
Environmental science and pollution research international 2023 Oct;30(48):106648-106659
Environmental science and pollution research international 2023 Oct;30(48):106648-106659
lncRNA GAS5 promotes pyroptosis in COPD by functioning as a ceRNA to regulate the miR‑223‑3p/NLRP3 axis.
Mo R, Li J, Chen Y, Ding Y
Molecular medicine reports 2022 Jul;26(1)
Molecular medicine reports 2022 Jul;26(1)
Azeliragon ameliorates Alzheimer's disease via the Janus tyrosine kinase and signal transducer and activator of transcription signaling pathway.
Yang L, Liu Y, Wang Y, Li J, Liu N
Clinics (Sao Paulo, Brazil) 2021;76:e2348
Clinics (Sao Paulo, Brazil) 2021;76:e2348
Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission.
Zhang XL, Huang WM, Tang PC, Sun Y, Zhang X, Qiu L, Yu BC, Zhang XY, Hong YX, He Y, Ge XQ
Neurotoxicology 2021 May;84:1-13
Neurotoxicology 2021 May;84:1-13
Programmed death-ligand 1 triggers PASMCs pyroptosis and pulmonary vascular fibrosis in pulmonary hypertension.
Zhang M, Xin W, Yu Y, Yang X, Ma C, Zhang H, Liu Y, Zhao X, Guan X, Wang X, Zhu D
Journal of molecular and cellular cardiology 2020 Jan;138:23-33
Journal of molecular and cellular cardiology 2020 Jan;138:23-33
Pre-administration of luteoline attenuates neonatal sevoflurane-induced neurotoxicity in mice.
Wang Y, Wang C, Zhang Y, Wang G, Yang H
Acta histochemica 2019 May;121(4):500-507
Acta histochemica 2019 May;121(4):500-507
Vector Analysis of Cytoskeletal Structural Tension and the Mechanisms that Underpin Spectrin-Related Forces in Pyroptosis.
Chen T, Guo Y, Shan J, Zhang J, Shen X, Guo J, Liu XM
Antioxidants & redox signaling 2019 Apr 20;30(12):1503-1520
Antioxidants & redox signaling 2019 Apr 20;30(12):1503-1520
Role of NLRP3 Inflammasome in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis with Nasal Polyps.
Lin H, Li Z, Lin D, Zheng C, Zhang W
Inflammation 2016 Dec;39(6):2045-2052
Inflammation 2016 Dec;39(6):2045-2052
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human liver, using Caspase-1 Antibody(M00048)CASP1 was detected in paraffin-embedded tissue section. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-CASP1 Antibody (M00048)overnight at 4
- Additional image
