ABIN499543

antibody from antibodies-online

Targeting: CASP1 ICE, IL1BC

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN499543

Provider

antibodies-online

Product name

anti-Caspase 1 (CASP1) (Intermediate Domain) antibody

Antibody type

Polyclonal

Antigen

Human Casp-1 / ICE / IL-1b converting enzyme (Intermediate Domain) Peptide (AP30188CP- N)

Description

Affinity chromatography purified via peptide column

Reactivity

Human

Host

Rabbit

Epitope

Intermediate Domain

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C.

References

Submitted references

Caspase-2 function in response to DNA damage.

Zhivotovsky B, Orrenius S
Biochemical and biophysical research communications 2005 Jun 10;331(3):859-67

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Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases.

Martinon F, Tschopp J
Cell 2004 May 28;117(5):561-74

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Interleukin-18.

Gracie JA, Robertson SE, McInnes IB
Journal of leukocyte biology 2003 Feb;73(2):213-24

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Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.

Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, Su MS, Flavell RA
Science (New York, N.Y.) 1995 Mar 31;267(5206):2000-3

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of Caspase-1 in HeLa cell lysate with AP30188PU-N Caspase-1 antibody (IN) at (A) 0.5, (B) 1, and (C) 2 ?g/ml.

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunohistochemistry of caspase-1 in human spleen tissue with AP30188PU-N caspase-1 antibody at 10 ?g/ml.