FNab01284

antibody from FineTest Biotech

Targeting: CASP1 ICE, IL1BC

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab01284 - Provider product page
Provider: FineTest Biotech
Product name: Caspase 1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: caspase 1, apoptosis-related cystei ne peptidase(interleukin 1, beta, c onvertase)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CASP1 protein structure - FNab01284 shown in red.