Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 19676-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19676-1-AP, RRID:AB_10640907
- Product name
- Integrin Alpha 4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Integrin Alpha 4 antibody (Cat. #19676-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.
Increased expression of cell adhesion molecules in myofasciitis.
Roles of cuproptosis-related gene DLAT in various cancers: a bioinformatic analysis and preliminary verification on pro-survival autophagy.
High Targeting Specificity toward Pulmonary Inflammation Using Mesenchymal Stem Cell-Hybrid Nanovehicle for an Efficient Inflammation Intervention.
Chidamide suppresses adipogenic differentiation of bone marrow derived mesenchymal stem cells via increasing REEP2 expression.
Cimigenol depresses acute myeloid leukemia cells protected by breaking bone marrow stromal cells via CXCR4/SDF‑1α.
Diethylaminoethyl-dextran and monocyte cell membrane coated 1,8-cineole delivery system for intracellular delivery and synergistic treatment of atherosclerosis.
Biomimetic liposomal nanozymes improve breast cancer chemotherapy with enhanced penetration and alleviated hypoxia.
Cell membrane-coated human hair nanoparticles for precise disease therapies.
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
Midkine mediates dysfunction of liver sinusoidal endothelial cells through integrin α4 and α6.
Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
Fe(3)O(4)@M nanoparticles for MRI-targeted detection in the early lesions of atherosclerosis.
Macrophage-cancer hybrid membrane-coated nanoparticles for targeting lung metastasis in breast cancer therapy.
Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease.
Membrane microvesicles as mediators for melanoma-fibroblasts communication: roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Zhou M, Wu Y, Sun M, Qin Y, Zhao J, Qiu Z, Li C, Zhang Y, Xiong Y, Shen Y, Zou Z, Tu J, Shen W, Sun C
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
Increased expression of cell adhesion molecules in myofasciitis.
Ma X, Gao H, Xu L, Bi Z, Ji S, Bu B
Frontiers in neurology 2023;14:1113404
Frontiers in neurology 2023;14:1113404
Roles of cuproptosis-related gene DLAT in various cancers: a bioinformatic analysis and preliminary verification on pro-survival autophagy.
Yang Q, Zeng S, Liu W
PeerJ 2023;11:e15019
PeerJ 2023;11:e15019
High Targeting Specificity toward Pulmonary Inflammation Using Mesenchymal Stem Cell-Hybrid Nanovehicle for an Efficient Inflammation Intervention.
Su Y, Huang T, Sun H, Lin R, Zheng X, Bian Q, Zhang J, Chen S, Wu H, Xu D, Zhang T, Gao J
Advanced healthcare materials 2023 Sep;12(23):e2300376
Advanced healthcare materials 2023 Sep;12(23):e2300376
Chidamide suppresses adipogenic differentiation of bone marrow derived mesenchymal stem cells via increasing REEP2 expression.
Zhang X, Liu L, Liu X, Huang Q, Liu L, Liu H, Ren S, Wei P, Cheng P, Yao M, Song W, Zhang H, Chen M
iScience 2023 Mar 17;26(3):106221
iScience 2023 Mar 17;26(3):106221
Cimigenol depresses acute myeloid leukemia cells protected by breaking bone marrow stromal cells via CXCR4/SDF‑1α.
Ma B, Dai H, Dai X, Qian S, Sha X, Sun X
Experimental and therapeutic medicine 2023 Feb;25(2):80
Experimental and therapeutic medicine 2023 Feb;25(2):80
Diethylaminoethyl-dextran and monocyte cell membrane coated 1,8-cineole delivery system for intracellular delivery and synergistic treatment of atherosclerosis.
Jiang F, Wu G, Yang H, Zhang Y, Shen X, Tao L
International journal of biological macromolecules 2023 Dec 31;253(Pt 7):127365
International journal of biological macromolecules 2023 Dec 31;253(Pt 7):127365
Biomimetic liposomal nanozymes improve breast cancer chemotherapy with enhanced penetration and alleviated hypoxia.
Li J, Gong C, Chen X, Guo H, Tai Z, Ding N, Gao S, Gao Y
Journal of nanobiotechnology 2023 Apr 10;21(1):123
Journal of nanobiotechnology 2023 Apr 10;21(1):123
Cell membrane-coated human hair nanoparticles for precise disease therapies.
Zhang Y, Li Y, Xia Q, Li Y, Jin S, Mao Q, Liu C, Fan X, Lin H
Journal of nanobiotechnology 2022 Nov 16;20(1):480
Journal of nanobiotechnology 2022 Nov 16;20(1):480
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model.
Tao X, Zhang R, Du R, Yu T, Yang H, Li J, Wang Y, Liu Q, Zuo S, Wang X, Lazarus M, Zhou L, Wang B, Yu Y, Shen Y
The Journal of experimental medicine 2022 May 2;219(5)
The Journal of experimental medicine 2022 May 2;219(5)
Midkine mediates dysfunction of liver sinusoidal endothelial cells through integrin α4 and α6.
Wu L, Chen H, Fu C, Xing M, Fang H, Yang F, Yang Q, Zhang Y, Li W, Chen Z
Vascular pharmacology 2022 Dec;147:107113
Vascular pharmacology 2022 Dec;147:107113
Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury.
Su VY, Chiou SH, Chen WC, Yu WK, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2021 May 24;22(11)
International journal of molecular sciences 2021 May 24;22(11)
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
Cvetanova B, Li MY, Yang CC, Hsiao PW, Yang YC, Feng JH, Shen YC, Nakagawa-Goto K, Lee KH, Shyur LF
International journal of molecular sciences 2021 Mar 22;22(6)
International journal of molecular sciences 2021 Mar 22;22(6)
Fe(3)O(4)@M nanoparticles for MRI-targeted detection in the early lesions of atherosclerosis.
Huang X, Lin C, Luo C, Guo Y, Li J, Wang Y, Xu J, Zhang Y, Wang H, Liu Z, Chen B
Nanomedicine : nanotechnology, biology, and medicine 2021 Apr;33:102348
Nanomedicine : nanotechnology, biology, and medicine 2021 Apr;33:102348
Macrophage-cancer hybrid membrane-coated nanoparticles for targeting lung metastasis in breast cancer therapy.
Gong C, Yu X, You B, Wu Y, Wang R, Han L, Wang Y, Gao S, Yuan Y
Journal of nanobiotechnology 2020 Jun 16;18(1):92
Journal of nanobiotechnology 2020 Jun 16;18(1):92
Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease.
Ohkuro M, Kim JD, Kuboi Y, Hayashi Y, Mizukami H, Kobayashi-Kuramochi H, Muramoto K, Shirato M, Michikawa-Tanaka F, Moriya J, Kozaki T, Takase K, Chiba K, Agarwala KL, Kimura T, Kotake M, Kawahara T, Yoneda N, Hirota S, Azuma H, Ozasa-Komura N, Ohashi Y, Muratani M, Kimura K, Hishinuma I, Fukamizu A
Nature communications 2018 May 17;9(1):1982
Nature communications 2018 May 17;9(1):1982
Membrane microvesicles as mediators for melanoma-fibroblasts communication: roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Zhao XP, Wang M, Song Y, Song K, Yan TL, Wang L, Liu K, Shang ZJ
Cancer letters 2015 May 1;360(2):125-33
Cancer letters 2015 May 1;360(2):125-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Integrin alpha-4 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Integrin alpha-4. This antibody recognizes human,mouse,rat antigen. The Integrin alpha-4 antibody has been validated for the following applications: ELISA, WB analysis.