TAB-022

antibody from Creative Biolabs

Targeting: ITGA4 CD49D

No application information provided.

Antibody Data

Product number

TAB-022

Provider

Creative Biolabs

Product name

Anti-Human ITGA4 Recombinant Antibody

Antibody type

Monoclonal

Description

Recombinant monoclonal antibody to Human ITGA4. Natalizumab is a humanized monoclonal antibody against the cell adhesion molecule ¦Á4-integrin. Natalizumab is used in the treatment of multiple sclerosis and Crohn's disease. Natalizumab is administered by intravenous infusion every 28 days. The drug is believed to work by reducing the ability of inflammatory immune cells to attach to and pass through the cell layers lining the intestines and blood¨Cbrain barrier. Natalizumab has proven effective in treating the symptoms of both diseases, preventing relapse, vision loss, cognitive decline and significantly improving quality of life in people with multiple sclerosis, as well as increasing rates of remission and preventing relapse in Crohn's disease.

Reactivity

Human

Isotype

IgG

Storage

At -20°ãC for one year.