RA0425

antibody from Oursmab

Targeting: ITGA4 CD49D

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0425

Provider

Oursmab

Product name

Abrilumab (Biosimilar Reference Antibody) (ITGA4B7)

Antibody type

Monoclonal

Description

Abrilumab is a fully human monoclonal antibody designed as a targeted therapy for inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. It functions as an antagonist that selectively blocks the ¦Á4¦Â7 integrin. By inhibiting this gut-specific adhesion molecule, abrilumab aims to prevent the trafficking and accumulation of pro-inflammatory lymphocytes in the intestinal tissue, thereby reducing local inflammation. Clinical development progressed to Phase II trials, but further advancement was discontinued.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.