20920-1-AP

antibody from Proteintech Group

Targeting: ITCH AIP4

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

20920-1-AP

Provider

Proteintech Group

Product name

ITCH antibody

Antibody type

Polyclonal

Description

ITCH antibody (Cat. #20920-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.

He J, Yi J, Ji L, Dai L, Chen Y, Xue W
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69

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Downregulation of TEX11 promotes S-Phase progression and proliferation in colorectal cancer cells through the FOXO3a/COP1/c-Jun/p21 axis.

Zhang X, Hu F, Zhu B, Jiao X, Li Y, Wu S, Ren G, Li J, Xie Q, Pan Y, Li H, Zhao L
Oncogene 2022 Nov;41(47):5133-5145

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ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3.

Zhou L, Song Z, Hu J, Liu L, Hou Y, Zhang X, Yang X, Chen K
Theranostics 2021;11(2):841-860

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Coiled-Coil Domain-Containing 68 Downregulation Promotes Colorectal Cancer Cell Growth by Inhibiting ITCH-Mediated CDK4 Degradation.

Wang C, Li H, Wu L, Jiao X, Jin Z, Zhu Y, Fang Z, Zhang X, Huang H, Zhao L
Frontiers in oncology 2021;11:668743

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GRAMD4 inhibits tumour metastasis by recruiting the E3 ligase ITCH to target TAK1 for degradation in hepatocellular carcinoma.

Ge QY, Chen J, Li GX, Tan XL, Song J, Ning D, Mo J, Du PC, Liu QM, Liang HF, Ding ZY, Zhang XW, Zhang BX
Clinical and translational medicine 2021 Nov;11(11):e635

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The E3 ubiquitin ligase Itch deficiency promotes antigen-driven B-cell responses in mice.

Fang Y, He Y, Zhai B, Hou C, Xu R, Xing C, Wang X, Ma N, Han G, Wang R
European journal of immunology 2021 Jan;51(1):103-114

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Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.

Zhang Y, Chen X, Wang Q, Du C, Lu W, Yuan H, Zhang Z, Li D, Ling X, Ren X, Zhao Y, Su Q, Xing Z, Qin Y, Yang X, Shen Y, Wu H, Qi Y
Journal of molecular medicine (Berlin, Germany) 2021 Dec;99(12):1797-1813

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JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling.

Ren Y, Chen D, Zhai Z, Chen J, Li A, Liang Y, Zhou J
Cell death discovery 2021 Apr 19;7(1):85

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ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia.

Ran J, Liu M, Feng J, Li H, Ma H, Song T, Cao Y, Zhou P, Wu Y, Yang Y, Yang Y, Yu F, Guo H, Zhang L, Xie S, Li D, Gao J, Zhang X, Zhu X, Zhou J
Developmental cell 2020 May 4;53(3):287-299.e5

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Heat stress activates YAP/TAZ to induce the heat shock transcriptome.

Luo M, Meng Z, Moroishi T, Lin KC, Shen G, Mo F, Shao B, Wei X, Zhang P, Wei Y, Guan KL
Nature cell biology 2020 Dec;22(12):1447-1459

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Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.

Wu L, Yuan W, Chen J, Zhou Z, Shu Y, Ji J, Liu Z, Tang Q, Zhang X, Shu X
Pediatric research 2019 Oct;86(4):460-470

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Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.

Yuan H, Xu J, Xu X, Gao T, Wang Y, Fan Y, Hu J, Shao Y, Zhao B, Li H, Sun J, Xu C
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344