Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN359074 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein Kinase C, theta (PRKCQ) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.
Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa activation.
Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta.
Protein kinase C theta modulates nuclear receptor-corepressor interaction during T cell activation.
Involvement of classical and novel protein kinase C isoforms in the response of human V gamma 9V delta 2 T cells to phosphate antigens.
Carrasco S, Merida I
Molecular biology of the cell 2004 Jun;15(6):2932-42
Molecular biology of the cell 2004 Jun;15(6):2932-42
Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa activation.
Sun L, Mao G, Rao AK
Blood 2004 Feb 1;103(3):948-54
Blood 2004 Feb 1;103(3):948-54
Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta.
Burchfield JG, Lennard AJ, Narasimhan S, Hughes WE, Wasinger VC, Corthals GL, Okuda T, Kondoh H, Biden TJ, Schmitz-Peiffer C
The Journal of biological chemistry 2004 Apr 30;279(18):18623-32
The Journal of biological chemistry 2004 Apr 30;279(18):18623-32
Protein kinase C theta modulates nuclear receptor-corepressor interaction during T cell activation.
Ishaq M, DeGray G, Natarajan V
The Journal of biological chemistry 2003 Oct 10;278(41):39296-302
The Journal of biological chemistry 2003 Oct 10;278(41):39296-302
Involvement of classical and novel protein kinase C isoforms in the response of human V gamma 9V delta 2 T cells to phosphate antigens.
Cipriani B, Knowles H, Chen L, Battistini L, Brosnan CF
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 15;169(10):5761-70
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 15;169(10):5761-70
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC