Tissue expression
Cell line expression
Protein structure
PRKCQ
Protein kinase C thetaProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
4 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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Cell Signaling Technology, Inc | ![]() |
Monoclonal |
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antibodies-online | ![]() |
5 references | Polyclonal |
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Abnova Corporation | ![]() |
3 references | Polyclonal |
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