Tissue expression
Cell line expression
Protein structure
PLA2G3
Phospholipase A2 group IIIGIII-SPLA2
This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]
Top validated antibodies |
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Biorbyt | orb2213583 | Polyclonal |
WB
ICC
IP
IHC |
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antibodies-online | ABIN4345945 | Polyclonal |
WB
IHC |
||
Abnova Corporation | H00050487-D01 | Polyclonal |
WB
IP |
||
Atlas Antibodies | HPA021016 | Polyclonal |
WB
IHC |
||
Novus Biologicals | NBP1-83367 | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider