TMTC4

This gene encodes a transmembrane protein that belongs to family of proteins containing an N-terminal transmembrane domain and a C-terminal tetratricopeptide repeat (TPR) domain. TPR domains mediate protein-protein interactions in various cellular processes, such as synaptic vesicle fusion, protein folding, and protein translocation. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Apr 2017]

Description

Transmembrane O-mannosyltransferase targeting cadherins 4

Tissue specificity

Tissue enhanced (brain)

Subcell location

Vesicles

Predicted location

Intracellular, Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

13 (100603625 - 100675093)

Ensembl ID

ENSG00000125247  (ver. 103.38)

Orthologs

Mouse Tmtc4: ENSMUSG00000041594

UniProt

Q5T4D3

neXtProt

NX_Q5T4D3

Human splice variants
Mouse splice variants

Protein structure