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- Antigen structure
- References [44]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10417-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10417-1-AP, RRID:AB_2263174
- Product name
- GATA3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GATA3 antibody (Cat. #10417-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GATA3-NLRP1 Axis Inhibits Hepatocellular Carcinoma Progression Through the Hedgehog Signaling.
Allele-specific knockdown by an engineered DNAzyme capable of RNase H1 evasion.
Growth hormone regulates deiodinase type 2 and 3 expression via GATA.
TGF-β induces a decrease in CAPZA1 expression to promote the invasiveness of hepatocellular carcinoma cells.
ADGRG6 Promotes Pancreatic Adenocarcinoma Progression Through the NF-κB/STAT6 Axis and Modulation of the Tumor Immune Microenvironment.
Aged mice-derived bronchial epithelial cells regulate Th17 cell differentiation in asthma via the MBD2-sICOSL axis.
Hyperactivity of the IL-33-ILC2s-IL-13-M-MDSCs axis promotes cervical cancer progression.
Inhibition of DNA Methyltransferase DNMT1 Reverses Th2 Response Polarisation and Alleviates Allergic Rhinitis.
Effect of 3D-Printed Polycaprolactone Scaffold With Powdery/Smooth Micromorphology on Local Immune Environments.
Electret-Inspired Charge-Injected Hydrogel for Scar-Free Healing of Bacterially Infected Burns Through Bioelectrical Stimulation and Immune Modulation.
Combination of androgen and estrogen improves asthma by mediating Runx3 expression.
Modulating Th1/Th2 drift in asthma-related immune inflammation by enhancing bone mesenchymal stem cell homing through targeted inhibition of the Notch1/Jagged1 signaling pathway.
Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats.
HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling.
Androgens have therapeutic potential in T2 asthma by mediating METTL3 in bronchial epithelial cells.
Skin Infiltrate Composition as a Telling Measure of Responses to Checkpoint Inhibitors.
PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway.
Androgen Plays a Potential Novel Hormonal Therapeutic Role in Th17 Cells Predominant Neutrophilic Severe Asthma by Attenuating BECs Regulated Th17 Cells Differentiation via MBD2 Expression.
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
Network pharmacology-based study on immunomodulatory mechanism of danggui-yimucao herb pair for the treatment of RU486-induced abortion.
Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.
Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma.
Huganbuzure Granule Attenuates Concanavalin-A-Induced Immune Liver Injury in Mice via Regulating the Balance of Th1/Th2/Th17/Treg Cells and Inhibiting Apoptosis.
Petroleum extract of Farfarae Flos alleviates nasal symptoms by regulating the Th1-Th2 cytokine balance in a mouse model of Allergic Rhinitis.
Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma.
mTOR pathway regulates the differentiation of peripheral blood Th2/Treg cell subsets in patients with pemphigus vulgaris.
Microenvironment Can Induce Development of Auditory Progenitor Cells from Human Gingival Mesenchymal Stem Cells.
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17.
Glycyrrhizic acid ammonium salt alleviates Concanavalin A-induced immunological liver injury in mice through the regulation of the balance of immune cells and the inhibition of hepatocyte apoptosis.
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
The histone acetyltransferase inhibitor Nir regulates epidermis development.
B Cell Presentation of Chlamydia Antigen Selects Out Protective CD4γ13 T Cells: Implications for Genital Tract Tissue-Resident Memory Lymphocyte Clusters.
Effects of Helicobacter pylori on the expression levels of GATA-3 and connexin 32 and the GJIC function in gastric epithelial cells and their association by promoter analysis.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
GATA3-driven expression of miR-503 inhibits prostate cancer progression by repressing ZNF217 expression.
Quantitative analysis of tissue inflammation and responses to treatment in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome, and review of literature.
Mature miR-183, negatively regulated by transcription factor GATA3, promotes 3T3-L1 adipogenesis through inhibition of the canonical Wnt/β-catenin signaling pathway by targeting LRP6.
CD4 T cells require ICOS-mediated PI3K signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy.
Endothelial microparticles exert differential effects on functions of Th1 in patients with acute coronary syndrome.
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Inhibition of Pim-1 kinase ameliorates dextran sodium sulfate-induced colitis in mice.
GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling.
Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.
Sun D, Sun X, Zhang J, Wang X, Liu L, Xie J, Song H
Cell biology international 2026 Jan;50(1):e70116
Cell biology international 2026 Jan;50(1):e70116
Allele-specific knockdown by an engineered DNAzyme capable of RNase H1 evasion.
Lee EM, Nguyen K, Setterholm NA, Malik TN, Chaput JC
Nucleic acids research 2026 Jan 5;54(1)
Nucleic acids research 2026 Jan 5;54(1)
Growth hormone regulates deiodinase type 2 and 3 expression via GATA.
Mitsutani M, Hano H, Yokoyama M, Matsushita M, Hayashi M, Yamauchi I, Tagami T, Moriyama K
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2025 Oct;82:101659
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2025 Oct;82:101659
TGF-β induces a decrease in CAPZA1 expression to promote the invasiveness of hepatocellular carcinoma cells.
Xiao L, Cao L, Luo Z, Zheng S, Huang D
The American journal of the medical sciences 2025 Nov;370(5):486-495
The American journal of the medical sciences 2025 Nov;370(5):486-495
ADGRG6 Promotes Pancreatic Adenocarcinoma Progression Through the NF-κB/STAT6 Axis and Modulation of the Tumor Immune Microenvironment.
Li L, Yu Z, Lu X, Yang P, Zhang S, Lin Q, Han J
Current issues in molecular biology 2025 Nov 27;47(12)
Current issues in molecular biology 2025 Nov 27;47(12)
Aged mice-derived bronchial epithelial cells regulate Th17 cell differentiation in asthma via the MBD2-sICOSL axis.
Chen Z, Shang Y, Yuan Y, Ji X, Gong S, Zeng Q, Xiang X
Cellular immunology 2025 May-Jun;411-412:104954
Cellular immunology 2025 May-Jun;411-412:104954
Hyperactivity of the IL-33-ILC2s-IL-13-M-MDSCs axis promotes cervical cancer progression.
Wang B, Zhu Y, Zhang Y, Ru Z, Chen L, Zhang M, Wu Y, Ding J, Chen Z
International immunopharmacology 2025 Jan 10;144:113693
International immunopharmacology 2025 Jan 10;144:113693
Inhibition of DNA Methyltransferase DNMT1 Reverses Th2 Response Polarisation and Alleviates Allergic Rhinitis.
Zou P, Li J, Li J, Wang J
Clinical and experimental pharmacology & physiology 2025 Feb;52(2):e70015
Clinical and experimental pharmacology & physiology 2025 Feb;52(2):e70015
Effect of 3D-Printed Polycaprolactone Scaffold With Powdery/Smooth Micromorphology on Local Immune Environments.
Hou L, Meng Z, Zhang J, Jiao Y, Chang K, He J, Zhang J
Journal of biomedical materials research. Part A 2025 Feb;113(2):e37869
Journal of biomedical materials research. Part A 2025 Feb;113(2):e37869
Electret-Inspired Charge-Injected Hydrogel for Scar-Free Healing of Bacterially Infected Burns Through Bioelectrical Stimulation and Immune Modulation.
Liu M, Wang Y, Wang H, Qi L, Shang Y, Song J, Feng X, Chen Y, Memon WA, Shen Y, Wu X, Cao J, Zhao Y, Jiang Z, Liu D, Shafique S, Li S, Lu G, Wei Z, Liu Z, Zhou K, Quan Y, Zhang X, Zou X, Wang X, Liu N, Zhang Y, Hu Y, Han C, Wang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411889
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2411889
Combination of androgen and estrogen improves asthma by mediating Runx3 expression.
He Y, Wasti B, Yuan Y, Chen Z, Duan W, Jia J, Xiao B, Zhang X, Li J, Zeng Q, Ma L, Liu S, Xiang X
International journal of medical sciences 2024;21(6):1003-1015
International journal of medical sciences 2024;21(6):1003-1015
Modulating Th1/Th2 drift in asthma-related immune inflammation by enhancing bone mesenchymal stem cell homing through targeted inhibition of the Notch1/Jagged1 signaling pathway.
Kun W, Xiaomei C, Lei Y, Huizhi Z
International immunopharmacology 2024 Mar 30;130:111713
International immunopharmacology 2024 Mar 30;130:111713
Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats.
Luo J, Liang C, Chen K, Zeng K, Bai R, Tang C, Li J, Nong X
BMC oral health 2024 Mar 20;24(1):356
BMC oral health 2024 Mar 20;24(1):356
HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling.
Qiu H, Shao Z, Wen X, Qu D, Liu Z, Chen Z, Zhang X, Ding X, Zhang L
Journal of translational medicine 2024 Jul 29;22(1):688
Journal of translational medicine 2024 Jul 29;22(1):688
Androgens have therapeutic potential in T2 asthma by mediating METTL3 in bronchial epithelial cells.
Chen Z, Shang Y, Duan W, Zhu L, Ji X, Gong S, Xiang X
International immunopharmacology 2024 Dec 25;143(Pt 1):113322
International immunopharmacology 2024 Dec 25;143(Pt 1):113322
Skin Infiltrate Composition as a Telling Measure of Responses to Checkpoint Inhibitors.
Kosche C, Jaishankar D, Cosgrove C, Ramesh P, Hong S, Li L, Shivde RS, Bhuva D, White BEP, Munir SS, Zhang H, Lu KQ, Choi JN, Le Poole IC
JID innovations : skin science from molecules to population health 2023 Sep;3(5):100190
JID innovations : skin science from molecules to population health 2023 Sep;3(5):100190
PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway.
Yu M, Tang W, Liang W, Xie B, Gao R, Ding P, Gu X, Wang M, Wen S, Sun P
International immunopharmacology 2023 Nov;124(Pt B):110962
International immunopharmacology 2023 Nov;124(Pt B):110962
Androgen Plays a Potential Novel Hormonal Therapeutic Role in Th17 Cells Predominant Neutrophilic Severe Asthma by Attenuating BECs Regulated Th17 Cells Differentiation via MBD2 Expression.
Wasti B, Chen Z, Yuan Y, He Y, Duan W, Jia J, Li D, Xiao B, Li J, Liu Y, Liu S, Zhang D, Zhang X, Ma L, Xiang X
Oxidative medicine and cellular longevity 2022;2022:3096528
Oxidative medicine and cellular longevity 2022;2022:3096528
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
Shi X, Zhao L, Niu L, Yan Y, Chen Q, Jin Y, Li X
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
Network pharmacology-based study on immunomodulatory mechanism of danggui-yimucao herb pair for the treatment of RU486-induced abortion.
Bi SJ, Huang YX, Feng LM, Yue SJ, Chen YY, Fu RJ, Xu DQ, Tang YP
Journal of ethnopharmacology 2022 Jan 10;282:114609
Journal of ethnopharmacology 2022 Jan 10;282:114609
Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer.
Ma Z, Li X, Mao Y, Wei C, Huang Z, Li G, Yin J, Liang X, Liu Z
Cancer cell 2022 Dec 12;40(12):1550-1565.e7
Cancer cell 2022 Dec 12;40(12):1550-1565.e7
Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma.
Zhao L, Zhang J, Xuan S, Liu Z, Wang Y, Zhao P
Frontiers in cell and developmental biology 2021;9:600506
Frontiers in cell and developmental biology 2021;9:600506
Huganbuzure Granule Attenuates Concanavalin-A-Induced Immune Liver Injury in Mice via Regulating the Balance of Th1/Th2/Th17/Treg Cells and Inhibiting Apoptosis.
Wang M, Yin H, Xia Y, Tu Y, Zou X, Song W, Luo L, Wu H, Yang Y, Zan J, Liu Y, Dan H, Yin Q, You P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5578021
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5578021
Petroleum extract of Farfarae Flos alleviates nasal symptoms by regulating the Th1-Th2 cytokine balance in a mouse model of Allergic Rhinitis.
Wu Y, Zhao X, Cui J, Guo Y, Zheng X, Zhang Y, Niu M, Li Z, Wen S, Gao W
International journal of medical sciences 2021;18(2):555-563
International journal of medical sciences 2021;18(2):555-563
Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma.
Yang B, Su Z, Chen G, Zeng Z, Tan J, Wu G, Zhu S, Lin L
Oncology letters 2021 Mar;21(3):180
Oncology letters 2021 Mar;21(3):180
mTOR pathway regulates the differentiation of peripheral blood Th2/Treg cell subsets in patients with pemphigus vulgaris.
Lai K, Zhang W, Li S, Zhang Z, Xie S, Xu M, Li C, Zeng K
Acta biochimica et biophysica Sinica 2021 Mar 26;53(4):438-445
Acta biochimica et biophysica Sinica 2021 Mar 26;53(4):438-445
Microenvironment Can Induce Development of Auditory Progenitor Cells from Human Gingival Mesenchymal Stem Cells.
Pouraghaei S, Moztarzadeh F, Chen C, Ansari S, Moshaverinia A
ACS biomaterials science & engineering 2020 Apr 13;6(4):2263-2273
ACS biomaterials science & engineering 2020 Apr 13;6(4):2263-2273
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17.
Liu D, He L, Ding N, Sun W, Qiu L, Xu L, Jia A, Peng C, Zhang D, Xiang X
Bioscience reports 2019 Feb 28;39(2)
Bioscience reports 2019 Feb 28;39(2)
Glycyrrhizic acid ammonium salt alleviates Concanavalin A-induced immunological liver injury in mice through the regulation of the balance of immune cells and the inhibition of hepatocyte apoptosis.
Tian X, Liu Y, Liu X, Gao S, Sun X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109481
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109481
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Xia Y, Yu B, Ma C, Tu Y, Zhai L, Yang Y, Liu D, Liu Y, Wu H, Dan H, You P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
The histone acetyltransferase inhibitor Nir regulates epidermis development.
Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Müller JM, Schüle R
Development (Cambridge, England) 2018 Mar 21;145(6)
Development (Cambridge, England) 2018 Mar 21;145(6)
B Cell Presentation of Chlamydia Antigen Selects Out Protective CD4γ13 T Cells: Implications for Genital Tract Tissue-Resident Memory Lymphocyte Clusters.
Johnson RM, Yu H, Strank NO, Karunakaran K, Zhu Y, Brunham RC
Infection and immunity 2018 Feb;86(2)
Infection and immunity 2018 Feb;86(2)
Effects of Helicobacter pylori on the expression levels of GATA-3 and connexin 32 and the GJIC function in gastric epithelial cells and their association by promoter analysis.
Huang L, Guo Y, Cao D, Liu X, Zhang L, Cao K, Hu T, Qi Y, Xu C
Oncology letters 2018 Aug;16(2):1650-1658
Oncology letters 2018 Aug;16(2):1650-1658
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression.
Guo S, Yang P, Jiang X, Li X, Wang Y, Zhang X, Sun B, Zhang Y, Jia Y
Oncotarget 2017 Jan 3;8(1):644-657
Oncotarget 2017 Jan 3;8(1):644-657
GATA3-driven expression of miR-503 inhibits prostate cancer progression by repressing ZNF217 expression.
Jiang X, Chen Y, Du E, Yang K, Zhang Z, Qi S, Xu Y
Cellular signalling 2016 Sep;28(9):1216-1224
Cellular signalling 2016 Sep;28(9):1216-1224
Quantitative analysis of tissue inflammation and responses to treatment in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome, and review of literature.
Chen CA, Chung WC, Chiou YY, Yang YJ, Lin YC, Ochs HD, Shieh CC
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2016 Oct;49(5):775-782
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2016 Oct;49(5):775-782
Mature miR-183, negatively regulated by transcription factor GATA3, promotes 3T3-L1 adipogenesis through inhibition of the canonical Wnt/β-catenin signaling pathway by targeting LRP6.
Chen C, Xiang H, Peng YL, Peng J, Jiang SW
Cellular signalling 2014 Jun;26(6):1155-65
Cellular signalling 2014 Jun;26(6):1155-65
CD4 T cells require ICOS-mediated PI3K signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy.
Chen H, Fu T, Suh WK, Tsavachidou D, Wen S, Gao J, Ng Tang D, He Q, Sun J, Sharma P
Cancer immunology research 2014 Feb;2(2):167-76
Cancer immunology research 2014 Feb;2(2):167-76
Endothelial microparticles exert differential effects on functions of Th1 in patients with acute coronary syndrome.
Lu Y, Li L, Yan H, Su Q, Huang J, Fu C
International journal of cardiology 2013 Oct 15;168(6):5396-404
International journal of cardiology 2013 Oct 15;168(6):5396-404
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Xu K, Usary J, Kousis PC, Prat A, Wang DY, Adams JR, Wang W, Loch AJ, Deng T, Zhao W, Cardiff RD, Yoon K, Gaiano N, Ling V, Beyene J, Zacksenhaus E, Gridley T, Leong WL, Guidos CJ, Perou CM, Egan SE
Cancer cell 2012 May 15;21(5):626-641
Cancer cell 2012 May 15;21(5):626-641
Inhibition of Pim-1 kinase ameliorates dextran sodium sulfate-induced colitis in mice.
Shen YM, Zhao Y, Zeng Y, Yan L, Chen BL, Leng AM, Mu YB, Zhang GY
Digestive diseases and sciences 2012 Jul;57(7):1822-31
Digestive diseases and sciences 2012 Jul;57(7):1822-31
GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling.
Froese N, Kattih B, Breitbart A, Grund A, Geffers R, Molkentin JD, Kispert A, Wollert KC, Drexler H, Heineke J
The Journal of biological chemistry 2011 Feb 18;286(7):5680-90
The Journal of biological chemistry 2011 Feb 18;286(7):5680-90
Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.
Adams JR, Xu K, Liu JC, Agamez NM, Loch AJ, Wong RG, Wang W, Wright KL, Lane TF, Zacksenhaus E, Egan SE
Cancer research 2011 Apr 1;71(7):2706-17
Cancer research 2011 Apr 1;71(7):2706-17
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10417-1-AP(GATA3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GATA3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GATA3. This antibody recognizes human, mouse, rat antigen. The GATA3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
