66400-1-Ig

antibody from Proteintech Group

Targeting: GATA3 HDR

Provider product page for 66400-1-Ig

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
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Product number: 66400-1-Ig - Provider product page
Provider: Proteintech Group
Product name: GATA3 antibody
Antibody type: Monoclonal
Description: GATA3 antibody (Cat. #66400-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1B11A8
Vial size: 20ul, 150ul

GATA3 protein structure - 66400-1-Ig shown in red.

Submitted references Renshen-Baidu-San restores epithelial-immune crosstalk and drives type 2 immune repair in ulcerative colitis: an integrated multi-omics study.

Liu J, Liu X, Zhang W, Song L, Xu Y, Yang Y, Xiong P, Jia B
Frontiers in immunology 2026;17:1777808

Single-cell RNA-seq reveals the immune profile changes in patients with diarrhoeal-irritable bowel syndrome.

Xue X, Hu J, Pei W, Mao T, Yuan Y, Zhang Y, Yao Y, Wang L, Xie C, Li J, Zhao X
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167945

Molecular and immune characteristics of neuroendocrine bladder carcinoma - Implications for diagnosis, prognosis, and therapy: A review.

Zhang T, Zhang X, Qian L, Hu C, Li J
Biomolecules & biomedicine 2025 Oct 9;26(5):711-719

Notoginsenoside R1 attenuates idiopathic pulmonary fibrosis through neuropilin-1/type 2 innate lymphoid cells pathway.

Yang M, Fang Y, Li X, Yang B, Ma Q, Cui X, Jiang L, Ge F
International immunopharmacology 2025 Oct 30;164:115385

MALAT1 elevates the secretion of Th2 cytokines via miR-422a/NUP155 axis in allergic rhinitis mice.

Zhang X, Yang R, Bai D, Liu M, Huang X, Wan W, Yang C
Archives of biochemistry and biophysics 2025 Nov;773:110603

Impact of innate lymphoid cell type 2 in chronic lymphocytic leukemia on the function of treg and CD8(+) T cells through IL-9.

Yang R, Zeng X, Alimu X, Qu J
Cancer immunology, immunotherapy : CII 2025 May 30;74(7):228

In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux.

Lv Y, Song B, Yang G, Wang Y, Wu Z, Si M, Yang Z, Chen H, Liu C, Li M, Zhang Y, Qiao Z, Wang L, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2409425

Prognostic value of LPAR1 expression and methylation in low-grade gliomas: a meta-analysis of TCGA and CGGA datasets and functional validation.

Chen H, Liang W, Li Z, Bian C, Wang H, Luo S, Xin Y, Feng W, Liang L
BMC cancer 2025 Dec 30;26(1):161

Tauroursodeoxycholic Acid Induces Liver Regeneration and Alleviates Fibrosis Through GATA3 Activation.

Bai C, Song X, Yan J, Xu J, Zhou Y, Sun Z, Zheng Q, Zhang Y, Chen R, Jin X, Shao Y, Xie Y, Yang L, Zhong F, Zhang Y, Li J, Li R, Yan S, Li X
Biomedicines 2025 Apr 9;13(4)

Pkd2l1 deletion inhibits the neurogenesis of cerebrospinal fluid-contacting neurons and impedes spinal cord injury repair.

Zhang Y, Cao L, Yan H, Luo Z, Chen C, Shangguan Z, Li Q, Shi X, Yang L, Tan W, Yang S, Fu J, Wang C, Dou X, Li Q
Cell death discovery 2025 Apr 23;11(1):194

The role of DNA damage response in human embryonic stem cells exposed to atmospheric oxygen tension: Implications for embryo development and differentiation.

Zhou Y, Ye F, Zhang L, Kang Q, Luo Y, Jiang N, Lou L, Mao Y, Wang L, Jin F
Reproductive toxicology (Elmsford, N.Y.) 2024 Sep;128:108648

A mannose-rich exopolysaccharide-1 isolated from Bifidobacterium breve mitigates ovalbumin-induced intestinal damage in mice by modulation CD4 + T cell differentiation and inhibiting NF-κB signaling pathway.

Niu MM, Li Y, Su Q, Chen SY, Li QH, Guo HX, Meng XC, Liu F
International journal of biological macromolecules 2024 Sep 24;280(Pt 3):135850

Gegen Qinlian decoction ameliorates TNBS-induced ulcerative colitis by regulating Th2/Th1 and Tregs/Th17 cells balance, inhibiting NLRP3 inflammasome activation and reshaping gut microbiota.

Hu Y, Tang J, Xie Y, Xu W, Zhu W, Xia L, Fang J, Yu D, Liu J, Zheng Z, Zhou Q, Shou Q, Zhang W
Journal of ethnopharmacology 2024 Jun 28;328:117956

Single-cell RNA-sequencing reveals the transcriptional landscape of lacrimal gland in GVHD mouse model.

He J, Zheng F, Zhang L, Cai J, Ogawa Y, Tsubota K, Liu S, Jin X
The ocular surface 2024 Jul;33:50-63

NPSR1 promotes chronic colitis through regulating CD4(+) T cell effector function in inflammatory bowel disease.

Peng Y, Chen L, Chen X, Lin J, Wei J, Cheng J, Zhou F, Ge L, Zhou R, Ding F, Wang X
International immunopharmacology 2024 Dec 5;142(Pt B):113252

BAG3 promotes proliferation and migration of arterial smooth muscle cells by regulating STAT3 phosphorylation in diabetic vascular remodeling.

Huang X, Guo J, Ning A, Zhang N, Sun Y
Cardiovascular diabetology 2024 Apr 25;23(1):140

METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.

Hu B, Zou X, Yu Y, Jiang Y, Xu H
Regenerative therapy 2023 Mar;22:148-159

GATA3 mediates doxorubicin resistance by inhibiting CYB5R2-catalyzed iron reduction in breast cancer cells.

Zhu Z, Shen H, Xu J, Fang Z, Wo G, Ma Y, Yang K, Wang Y, Yu Q, Tang JH
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Jul;69:100974

Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.

Shen Y, Xu S, Ye C, Li Q, Chen R, Wu W, Jiang Q, Jia Y, Zhang X, Fan L, Fu W, Jiang M, Chen J, Timko MP, Zhao P, Ruan J
iScience 2023 Feb 17;26(2):106003

Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.

Li Z, Ma D, Wang Y, Wu S, Wang L, Jiang Y, Zhang Y, Li X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7421265

Acupoint Autohemotherapy Attenuates Atopic Dermatitis Lesions by Regulating Th1/Th2 Balance in DNCB-Induced BALB/c Mice.

Zeng ZW, Huang JQ, Chen Y, Yu X, Zhu W, Zhang DS
Chinese journal of integrative medicine 2022 Jul;28(7):612-619

Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.

Coelho DR, Palma FR, Paviani V, He C, Danes JM, Huang Y, Calado JCP, Hart PC, Furdui CM, Poole LB, Schipma MJ, Bonini MG
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 19;119(29):e2110348119

Lack of WDFY4 Aggravates Ovalbumin-Induced Asthma via Enhanced Th2 Cell Differentiation.

Li Y, Wang A, Long F, Gao F, Gao S, Wei S, Liu A, Li X, Sun W, Li J, Liu Q
International archives of allergy and immunology 2021;182(11):1089-1096

Modified BuShenYiQi formula alleviates experimental allergic asthma in mice by negative regulation of type 2 innate lymphoid cells and CD4(+) type 9 helper T cells and the VIP-VPAC2 signalling pathway.

Huang M, Wu J, Dong J
Pharmaceutical biology 2021 Dec;59(1):1216-1232

Therapeutic effects and mechanisms study of Hanchuan Zupa Granule in a Guinea pig model of cough variant asthma.

Li P, Wang J, Wang C, Cheng L, Ma Q, Li Y, An Y, Dai H, Duan Y, Wang T, Ma X, Zhang M, Wang T, Zhao B
Journal of ethnopharmacology 2021 Apr 6;269:113719

RANK promotes colorectal cancer migration and invasion by activating the Ca(2+)-calcineurin/NFATC1-ACP5 axis.

Liang Q, Wang Y, Lu Y, Zhu Q, Xie W, Tang N, Huang L, An T, Zhang D, Yan A, Liu S, Ye L, Zhu C
Cell death & disease 2021 Apr 1;12(4):336

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