Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14597-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14597-1-AP, RRID:AB_2117919
- Product name
- HMGB2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HMGB2 antibody (Cat. #14597-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LncRNA SNHG16 accelerates atherosclerosis and promotes ox-LDL-induced VSMC growth via the miRNA-22-3p/HMGB2 axis.
Nuclear exosome HMGB3 secreted by nasopharyngeal carcinoma cells promotes tumour metastasis by inducing angiogenesis.
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
Fluoride-induced unrestored arrest during haploid period of spermatogenesis via the regulation of DDX25 in rats.
HMGB2 promotes the malignancy of human gastric cancer and indicates poor survival outcome.
HMGB2 is associated with malignancy and regulates Warburg effect by targeting LDHB and FBP1 in breast cancer.
Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells.
Wang Y, Yang Y, Zhang T, Jia S, Ma X, Zhang M, Wang L, Ma A
European journal of pharmacology 2022 Jan 15;915:174601
European journal of pharmacology 2022 Jan 15;915:174601
Nuclear exosome HMGB3 secreted by nasopharyngeal carcinoma cells promotes tumour metastasis by inducing angiogenesis.
Zhang K, Liu D, Zhao J, Shi S, He X, Da P, You Y, You B
Cell death & disease 2021 May 28;12(6):554
Cell death & disease 2021 May 28;12(6):554
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Wang F, Luo Y, Zhang L, Younis M, Yuan L
Cancer gene therapy 2021 Mar 11;
Cancer gene therapy 2021 Mar 11;
Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
Han Y, Liang C, Manthari RK, Yu Y, Gao Y, Liu Y, Jiang S, Tikka C, Wang J, Zhang J
Chemosphere 2020 Jan;238:124650
Chemosphere 2020 Jan;238:124650
Fluoride-induced unrestored arrest during haploid period of spermatogenesis via the regulation of DDX25 in rats.
Han Y, Yu Y, Liang C, Shi Y, Zhu Y, Zheng H, Wang J, Zhang J
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:538-551
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:538-551
HMGB2 promotes the malignancy of human gastric cancer and indicates poor survival outcome.
Cui G, Cai F, Ding Z, Gao L
Human pathology 2019 Feb;84:133-141
Human pathology 2019 Feb;84:133-141
HMGB2 is associated with malignancy and regulates Warburg effect by targeting LDHB and FBP1 in breast cancer.
Fu D, Li J, Wei J, Zhang Z, Luo Y, Tan H, Ren C
Cell communication and signaling : CCS 2018 Feb 20;16(1):8
Cell communication and signaling : CCS 2018 Feb 20;16(1):8
Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
Cai X, Ding H, Liu Y, Pan G, Li Q, Yang Z, Liu W
Acta biochimica et biophysica Sinica 2017 Feb 6;49(2):119-127
Acta biochimica et biophysica Sinica 2017 Feb 6;49(2):119-127
Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells.
Abraham AB, Bronstein R, Chen EI, Koller A, Ronfani L, Maletic-Savatic M, Tsirka SE
Proteome science 2013 Apr 27;11(1):18
Proteome science 2013 Apr 27;11(1):18
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 14597-1-AP(HMGB2 antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 14597-1-AP(HMGB2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HMGB2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HMGB2. This antibody recognizes human,mouse,rat antigen. The HMGB2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.