BS8740

antibody from Bioworld Technology, Inc
Targeting: CARD11 BIMP3, CARMA1
Provider product page for BS8740
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8740 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CARD11 polyclonal antibody
Antibody type
Polyclonal
Antigen
Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 1; Carma 1; CARD11; CARMA1
Description
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CARD11 protein structure - BS8740 shown in red.