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Protein structure
CARD11
Caspase recruitment domain family member 11BIMP3, CARMA1
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  21741-1-AP |
3 references | Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C346250 |
Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NB100-1200 |
2 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN499539 |
4 references | Polyclonal |
WB
EL
IHC
|
|
| Atlas Antibodies | HPA052984 |
1 references | Polyclonal |
WB
IHC
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