Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 18322-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18322-1-AP, RRID:AB_2139251
- Product name
- MAD1 antibody
- Antibody type
- Polyclonal
- Description
- MAD1 antibody (Cat. #18322-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.
Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility.
ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint.
TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction.
Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53.
Luo H, Huang K, Cheng M, Long X, Zhu X, Wu M
Aging 2023 Oct 17;15(20):11052-11066
Aging 2023 Oct 17;15(20):11052-11066
Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility.
Villarroya-Beltri C, Osorio A, Torres-Ruiz R, Gómez-Sánchez D, Trakala M, Sánchez-Belmonte A, Mercadillo F, Hurtado B, Pitarch B, Hernández-Núñez A, Gómez-Caturla A, Rueda D, Perea J, Rodríguez-Perales S, Malumbres M, Urioste M
Science advances 2022 Nov 4;8(44):eabq5914
Science advances 2022 Nov 4;8(44):eabq5914
ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint.
Yuan F, Jin X, Li D, Song Y, Zhang N, Yang X, Wang L, Zhu WG, Tian C, Zhao Y
Nucleic acids research 2019 Sep 5;47(15):8096-8110
Nucleic acids research 2019 Sep 5;47(15):8096-8110
TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction.
Shen S, Zuo J, Feng H, Bai M, Wang C, Wei Y, Li Y, Le Y, Wu J, Wu Y, Yu L
BMB reports 2016 Jun;49(6):325-30
BMB reports 2016 Jun;49(6):325-30
Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53.
Reed SM, Hagen J, Tompkins VS, Thies K, Quelle FW, Quelle DE
Cell cycle (Georgetown, Tex.) 2014;13(8):1288-98
Cell cycle (Georgetown, Tex.) 2014;13(8):1288-98
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 18322-1-AP(MAD1L1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 18322-1-AP(MAD1L1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MAD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MAD1. This antibody recognizes human,mouse,rat antigen. The MAD1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.