MAD1L1

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Description

mitotic arrest deficient 1 like 1

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

7:p22.3 (1815793 - 2233243)

Ensembl ID

ENSG00000002822  (ver. 99.38)

Orthologs

Mouse Mad1l1: ENSMUSG00000029554

UniProt

Q9Y6D9

neXtProt

NX_Q9Y6D9

Human splice variants
Mouse splice variants