EMP2

gene product
XMP
This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progression in multiple different tissues. Mutations in this gene have been associated with nephrotic syndrome type 10 (NPHS10). [provided by RefSeq, Mar 2015]
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139 antibodies from 22 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Novus Biologicals
2 antibodies
antibodies-online
32 antibodies
Invitrogen Antibodies
3 antibodies
Biorbyt
11 antibodies
NovoPro Bioscience Inc.
1 antibody
LifeSpan BioSciences, Inc.
24 antibodies
Aviva Systems Biology
2 antibodies
OriGene
2 antibodies
Abgent
1 antibody
GeneTex
1 antibody
ProSci
2 antibodies
Boster Biological Technology
1 antibody
Abnova Corporation
2 antibodies
Creative Biolabs
20 antibodies
MyBioSource
3 antibodies
United States Biological
13 antibodies
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies
RayBiotech, Inc.
1 antibody
GenWay
1 antibody