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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 55260-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55260-1-AP, RRID:AB_10973676
- Product name
- VDAC3 antibody
- Antibody type
- Polyclonal
- Description
- VDAC3 antibody (Cat. #55260-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers.
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes.
De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence.
The genomic signature of resistance to platinum-containing neoadjuvant therapy based on single-cell data.
Prevotella histicola suppresses ferroptosis to mitigate ethanol-induced gastric mucosal lesions in mice.
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
Proteomic Studies of the Mechanism of Cytotoxicity, Induced by Palytoxin on HaCaT Cells.
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress.
Tang Y, Wu J, Sun X, Tan S, Li W, Yin S, Liu L, Chen Y, Liu Y, Tan Q, Jiang Y, Yang W, Huang W, Weng C, Wu Q, Lu Y, Yuan H, Xiao Q, Chen AF, Xu Q, Billiar TR, Cai J
Cell reports 2024 May 28;43(5):114237
Cell reports 2024 May 28;43(5):114237
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers.
Lei G, Mao C, Horbath AD, Yan Y, Cai S, Yao J, Jiang Y, Sun M, Liu X, Cheng J, Xu Z, Lee H, Li Q, Lu Z, Zhuang L, Chen MK, Alapati A, Yap TA, Hung MC, You MJ, Piwnica-Worms H, Gan B
Cancer discovery 2024 Aug 2;14(8):1476-1495
Cancer discovery 2024 Aug 2;14(8):1476-1495
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
Zhang T, Cao RJ, Niu JL, Chen ZH, Mu SQ, Cao T, Pang JX, Dong LH
Cellular & molecular biology letters 2024 Apr 8;29(1):47
Cellular & molecular biology letters 2024 Apr 8;29(1):47
Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes.
Deisl C, Chung JH, Hilgemann DW
The Journal of general physiology 2023 Oct 2;155(10)
The Journal of general physiology 2023 Oct 2;155(10)
De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence.
Yang C, Zhao Y, Wang L, Guo Z, Ma L, Yang R, Wu Y, Li X, Niu J, Chu Q, Fu Y, Li B
Nature cell biology 2023 Jun;25(6):836-847
Nature cell biology 2023 Jun;25(6):836-847
The genomic signature of resistance to platinum-containing neoadjuvant therapy based on single-cell data.
Sui Q, Hu Z, Jin X, Bian Y, Liang J, Zhang H, Yang H, Lin Z, Wang Q, Zhan C, Chen Z
Cell & bioscience 2023 Jun 8;13(1):103
Cell & bioscience 2023 Jun 8;13(1):103
Prevotella histicola suppresses ferroptosis to mitigate ethanol-induced gastric mucosal lesions in mice.
Wang S, Wu D, Wu F, Sun H, Wang X, Meng H, Lin Q, Jin K, Wang F
BMC complementary medicine and therapies 2023 Apr 14;23(1):118
BMC complementary medicine and therapies 2023 Apr 14;23(1):118
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
Huang G, Xiang Z, Wu H, He Q, Dou R, Lin Z, Yang C, Huang S, Song J, Di Z, Wang S, Xiong B
International journal of biological sciences 2022;18(4):1415-1433
International journal of biological sciences 2022;18(4):1415-1433
Proteomic Studies of the Mechanism of Cytotoxicity, Induced by Palytoxin on HaCaT Cells.
Cheng D, Deng B, Tong Q, Gao S, Xiao B, Zhu M, Ren Z, Wang L, Sun M
Toxins 2022 Apr 10;14(4)
Toxins 2022 Apr 10;14(4)
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
Zhu T, Liu B, Wu D, Xu G, Fan Y
Frontiers in cell and developmental biology 2021;9:740884
Frontiers in cell and developmental biology 2021;9:740884
Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress.
Yang M, Sun J, Stowe DF, Tajkhorshid E, Kwok WM, Camara AKS
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2020 Sep 9;54(5):853-874
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2020 Sep 9;54(5):853-874
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 55260-1-AP(VDAC3 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 55260-1-AP(VDAC3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VDAC3 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human VDAC3. This antibody recognizes human, mouse, rat antigen. The VDAC3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
