23288-1-AP

antibody from Proteintech Group

Targeting: TICAM1 MGC35334, PRVTIRB, TICAM-1, TRIF

Provider product page for 23288-1-AP

Western blot

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Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [28]
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Product number: 23288-1-AP - Provider product page
Provider: Proteintech Group
Product name: TRIF/TICAM1 antibody
Antibody type: Polyclonal
Description: TRIF/TICAM1 antibody (Cat. #23288-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

TICAM1 protein structure - 23288-1-AP shown in red.

Submitted references Total tanshinones extract alleviates chronic prostatitis/chronic pelvic pain syndrome by modifying intestinal flora and suppressing the LPS-TLR4 axis.

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Poly-IC Alleviates Nitroglycerin-Induced Migraine by Inhibiting Neuroinflammation via TLR3/TRIF Signaling Pathway.

Hong Y, Ma M, Li C, Zhang Y, Li Y, Chen N, Fang J, He L
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PCSK9 Enhances Cardiac Fibrogenesis via the Activation of Toll-like Receptor and NLRP3 Inflammasome Signaling.

Chung CC, Kao YH, Chen YC, Lin YK, Higa S, Hsu KC, Chen YJ
International journal of molecular sciences 2025 Feb 23;26(5)

HSYA targets the ZBP1-166R site to inhibit MAVS signaling: A potential therapeutic strategy for cerebral ischemia-reperfusion injury.

Sun H, Zhu K, Peng Y, Zhou X, Chang D, Wang N, Huang P
Cellular signalling 2025 Dec;136:112138

Nanomedicine-mediated macrophage polarization enhances the iron-depleting effect of desferrioxamine for breast cancer immunotherapy.

Chen S, Yin W, Zhi H, Zhang X, An L, Yang Z, Li R, Cai Y, You C, Li Y, Li Y, Dong H
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Lipopolysaccharide Induces Resistance to CAR-T Cell Therapy of Colorectal Cancer Cells through TGF-β-Mediated Stemness Enhancement.

Tao M, Xue M, Zhou D, Zhang L, Hou X, Zhu X, Feng S, Yan H, Qian X, Wei L, Zong C, Yang X, Zhang L
Molecular pharmaceutics 2025 Apr 7;22(4):1790-1803

PPARα affects hepatic lipid homeostasis by perturbing necroptosis signals in the intestinal epithelium.

Na S, Fan Y, Chen H, Li L, Li G, Zhang F, Wang R, Yang Y, Shen Z, Peng Z, Wu Y, Zhu Y, Yang Z, Dong G, Ye Q, Yue J
Acta pharmaceutica Sinica. B 2024 Nov;14(11):4858-4873

TBK1 pharmacological inhibition mitigates osteoarthritis through attenuating inflammation and cellular senescence in chondrocytes.

Lu R, Qu Y, Wang Z, He Z, Xu S, Cheng P, Lv Z, You H, Guo F, Chen A, Zhang J, Liang S
Journal of orthopaedic translation 2024 Jul;47:207-222

Gut-derived 4-hydroxyphenylacetic acid attenuates sepsis-induced acute kidney injury by upregulating ARC to inhibit necroptosis.

An S, Yao Y, Wu J, Hu H, Wu J, Sun M, Li J, Zhang Y, Li L, Qiu W, Li Y, Deng Z, Fang H, Gong S, Huang Q, Chen Z, Zeng Z
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Manganese@Albumin Nanocomplex and Its Assembled Nanowire Activate TLR4-Dependent Signaling Cascades of Macrophages.

Huang S, Gao Y, Li H, Wang R, Zhang X, Wang X, Huang D, Zhang L, Santos HA, Yin Z, Xia B
Advanced materials (Deerfield Beach, Fla.) 2024 Feb;36(5):e2310979

Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Validation.

Xu Y, Cai Q, Zhao C, Zhang W, Xu X, Lin H, Lin Y, Chen D, Lin S, Jia P, Wang M, Zhang L, Lin W
Pharmaceuticals (Basel, Switzerland) 2024 Dec 25;18(1)

Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.

Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198

Cisatracurium besylate rescues Mycobacterium Tuberculosis-infected macrophages from necroptosis and enhances the bactericidal effect of isoniazid.

Wen Q, Zhang J, Zhang Z, Chen L, Liu H, Han Z, Chen Y, Wang K, Liu J, Sai N, Zhou X, Zhou C, Hu S, Ma L
International immunopharmacology 2023 Jul;120:110291

Digestibility of Malondialdehyde-Induced Dietary Advanced Lipoxidation End Products and Their Effects on Hepatic Lipid Accumulation in Mice.

Wang Y, Zhang T, Nie L, Zhang Y, Wang J, Liu Q, Dong L, Hu Y, Zhang B, Wang S
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10403-10416

Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway.

Yang J, Kou X
Autoimmunity 2023 Dec;56(1):2182741

Spatiotemporal expression patterns of ZBP1 in the brain of mouse experimental stroke model.

Mutoh T, Kikuchi H, Jitsuishi T, Kitajo K, Yamaguchi A
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SARS-CoV-2 NSP8 suppresses type I and III IFN responses by modulating the RIG-I/MDA5, TRIF, and STING signaling pathways.

Deng J, Zheng SN, Xiao Y, Nan ML, Zhang J, Han L, Zheng Y, Yu Y, Ding Q, Gao C, Wang PH
Journal of medical virology 2023 Apr;95(4):e28680

Lycopene-Loaded Bilosomes Ameliorate High-Fat Diet-Induced Chronic Nephritis in Mice through the TLR4/MyD88 Inflammatory Pathway.

Liu C, Liu Y, Wang C, Guo Y, Cheng Y, Qian H, Zhao Y
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Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.

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Metabolites 2022 Nov 17;12(11)

The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis.

Erttmann SF, Swacha P, Aung KM, Brindefalk B, Jiang H, Härtlova A, Uhlin BE, Wai SN, Gekara NO
Immunity 2022 May 10;55(5):847-861.e10

Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line.

Tu Y, Yang Y, Wang Y, Wu N, Tao J, Yang G, You M
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120217

TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38(-/-) Sepsis Mice.

Zhang H, Du Y, Guo Y, Wang Z, Li H, Lv Z, Zeng L, Chen Y, Xie Z, Li R
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Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity.

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Frontiers in immunology 2021;12:755961

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Xu Y, Chen Y, Liu H, Lei X, Guo J, Cao K, Liu C, Li B, Cai J, Ju J, Gao F, Yang Y
Oncotarget 2017 Sep 15;8(40):67082-67093

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