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TICAM1
Toll like receptor adaptor molecule 1MGC35334, PRVTIRB, TICAM-1, TRIF
This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. Mutations in this gene are associated with encephalopathy, acute, infection-induced. [provided by RefSeq, Jul 2020]
Top validated antibodies |
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| Novus Biologicals |  NB120-13810 |
30 references | Polyclonal |
WB
ICC
IP
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| Proteintech Group | 23288-1-AP |
19 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN266066 |
26 references | Polyclonal |
WB
ICC
IP
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| LSBio | LS-C313040 |
Polyclonal |
WB
IHC
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| Boster Biological Technology | A01872-1 |
1 references | Polyclonal |
WB
EL
FC
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