Ab132451

antibody from Aladdin Scientific

Targeting: TICAM1 MGC35334, PRVTIRB, TICAM-1, TRIF

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Validation data

Product number: Ab132451 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant TRIF Antibody
Antibody type: Recombinant
Description: Rabbit anti Human TRIF Antibody, Recombinant (R02-2A9), could be used for WB and so on.Application:WB: 1/500 – 1/1000Protein FunctionInvolved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 512-712
Antibody clone number: R02-2A9
Vial size: 100μl,10μl,1ml,50μl
Concentration: 0,6 mg/ml
Storage: Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

TICAM1 protein structure - Ab132451 shown in red.